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1. (WO2019064263) NOVEL FORMULATIONS WHICH STABILIZE LOW DOSE ANTIBODY COMPOSITIONS
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Pub. No.: WO/2019/064263 International Application No.: PCT/IB2018/057565
Publication Date: 04.04.2019 International Filing Date: 28.09.2018
IPC:
C07K 16/28 (2006.01) ,A61K 39/395 (2006.01) ,A61K 47/26 (2006.01) ,C23C 16/00 (2006.01) ,C03C 17/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
C CHEMISTRY; METALLURGY
23
COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
C
COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
16
Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes
C CHEMISTRY; METALLURGY
03
GLASS; MINERAL OR SLAG WOOL
C
CHEMICAL COMPOSITION OF GLASSES, GLAZES, OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
17
Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating
Applicants:
JANSSEN BIOTECH, INC. [US/US]; 800/850 Ridgeview Drive Horsham, PA 19044, US
Inventors:
MACKAY, Joanna; US
Agent:
SHIRTZ, Joseph F.; US
BAUMEISTER, Kirk; US
Priority Data:
62/565,17829.09.2017US
Title (EN) NOVEL FORMULATIONS WHICH STABILIZE LOW DOSE ANTIBODY COMPOSITIONS
(FR) NOUVELLES FORMULATIONS PERMETTANT DE STABILISER DES COMPOSITIONS D'ANTICORPS À FAIBLE DOSE
Abstract:
(EN) The present invention addresses an ongoing need in the art to improve the stability of antibody compositions. The invention broadly relates to novel formulations which stabilize and inhibit protein adsorption of low dose antibody compositions in a container means comprising a coating. More particularly, the invention described hereinafter, addresses a need in the art for formulations which stabilize and inhibit protein adsorption of low dose antibody compositions which are processed, developed, formulated, manufactured and/or stored in container means such as fermentors, bioreactors, vials, flasks, bags, syringes, rubber stoppers, tubing and the like.
(FR) L'objectif de la présente invention concerne le besoin constaté dans l'état de la technique afin d'améliorer la stabilité de compositions d'anticorps. L'invention concerne d'une manière générale de nouvelles formulations permettant de stabiliser et d'inhiber l'adsorption protéique de compositions d'anticorps à faible dose dans un moyen de contenant comprenant un revêtement. L'invention concerne, plus particulièrement, le besoin dans l'état de la technique pour des formulations permettant de stabiliser et d'inhiber l'adsorption protéique de compositions d'anticorps à faible dose qui sont traitées, développées, formulées, fabriquées et/ou stockées dans des moyens de contenant tels que des fermenteurs, des bioréacteurs, des fioles, des flacons, des sacs, des seringues, des bouchons en caoutchouc, des tubulures et analogues.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)