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1. (WO2019064136) EEG MICROSTATES ANALYSIS
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Pub. No.: WO/2019/064136 International Application No.: PCT/IB2018/057280
Publication Date: 04.04.2019 International Filing Date: 21.09.2018
IPC:
A61B 5/04 (2006.01) ,A61B 5/02 (2006.01) ,A61B 5/00 (2006.01) ,G06F 19/00 (2018.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
04
Measuring bioelectric signals of the body or parts thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
02
Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
B
DIAGNOSIS; SURGERY; IDENTIFICATION
5
Measuring for diagnostic purposes; Identification of persons
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
F
ELECTRIC DIGITAL DATA PROCESSING
19
Digital computing or data processing equipment or methods, specially adapted for specific applications
Applicants:
MOR RESEARCH APPLICATIONS LTD. [IL/IL]; 38 Habarzel St. 6971054 Tel Aviv, IL
RAMOT AT TEL-AVIV UNIVERSITY LTD. [IL/IL]; Tel Aviv University Campus The Senate Building, Floor-1 P.O. Box 39296 6139201 Tel Aviv, IL
Inventors:
GLIK, Amir; IL
FURST-YUST, Miriam; IL
BENNINGER, Felix; IL
Agent:
RICHTER, Allen; IL
SHIMONI, Gila; IL
Priority Data:
62/652,36104.04.2018US
PCT/IB2017/05589927.09.2017IB
Title (EN) EEG MICROSTATES ANALYSIS
(FR) ANALYSE DE MICRO-ÉTATS D'EEG
Abstract:
(EN) Using microstate data to evaluate Alzheimer's disease including dementia and/or mild cognitive impairment and/or depression and optionally provide treatment based on the diagnosis and/or modify treatment and/or diagnosis based on response to treatment, optionally as measured using microstate data. In one example, the method includes analyzing EEG data to generate one or more EEG parameter; and generating a risk for one or both of depression and MCI (mild cognitive impairment) based on said one or more EEG parameters. Optionally, the disease comprises MCI. Optionally, the disease comprises depression. Optionally, the one or more EEG parameter comprises a microstate-derived parameter. Optionally, the one or more EEG parameter comprises a microstate duration derived parameter.
(FR) La présente invention concerne l'utilisation de données de micro-état pour évaluer la maladie d'Alzheimer comprenant la démence et/ou la déficience cognitive légère et/ou la dépression et éventuellement fournir un traitement sur la base du diagnostic et/ou modifier le traitement et/ ou un diagnostic sur la base d'une réponse au traitement, éventuellement telle que mesurée à l'aide de données de micro-état. Dans un exemple, le procédé comprend l'analyse de données d'EEG pour générer un ou plusieurs paramètres d'EEG ; et la génération d'un risque pour la dépression ou le MCI (trouble cognitif léger) ou les deux sur la base dudit ou desdits paramètres de l'EEG. Facultativement, la maladie comprend un MCI. Facultativement, la maladie comprend la dépression. Facultativement, le ou les paramètres de l'EEG comprennent un paramètre dérivé d'un micro-état. Facultativement, le ou les paramètres de l'EEG comprennent un paramètre dérivé de durée de micro-état.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)