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1. (WO2019063958) BIOCONJUGATION OF POLYPEPTIDES
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Pub. No.: WO/2019/063958 International Application No.: PCT/GB2017/052896
Publication Date: 04.04.2019 International Filing Date: 27.09.2017
IPC:
C07K 1/107 (2006.01) ,C07K 1/13 (2006.01) ,A61K 47/54 (2017.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
107
by chemical modification of precursor peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
1
General processes for the preparation of peptides
13
Labelling of peptides
[IPC code unknown for A61K 47/54]
Applicants:
THE UNIVERSITY OF YORK [GB/GB]; Heslington, Heslington York North Yorkshire YO10 5DD, GB
Inventors:
FASCIONE, Martin A.; GB
SPEARS, Richard J.; GB
BRABHAM, Robin; GB
BUDHADEV, Darshita; GB
KEENAN, Tessa; GB
Agent:
SECERNA LLP; The Catalyst Baird Lane Heslington Easy, Heslington East York North Yorkshire YO10 5GA, GB
Priority Data:
Title (EN) BIOCONJUGATION OF POLYPEPTIDES
(FR) BIOCONJUGAISON DE POLYPEPTIDES
Abstract:
(EN) Certain embodiments of the present invention relate to methods of forming and manipulating bioconjugates. Particularly, but not exclusively certain embodiments relate to methods of reversible carbon-carbon bond bioconjugation using aldol based chemical reactions at physiological conditions.
(FR) Selon certains modes de réalisation, la présente invention concerne des procédés de formation et de manipulation de bioconjugués. En particulier, mais sans caractère exclusive, certains modes de réalisation de la présente invention concernent des procédés de bioconjugaison de liaison carbone-carbone réversible utilisant des réactions chimiques à base d'aldol dans des conditions physiologiques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)