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1. (WO2019063735) CAPTOPRIL LIQUID DOSAGE FORM AND DELIVERY SYSTEM
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Pub. No.: WO/2019/063735 International Application No.: PCT/EP2018/076358
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
A61K 47/26 (2006.01) ,A61K 47/36 (2006.01) ,A61K 9/10 (2006.01) ,A61K 9/14 (2006.01) ,A61K 31/00 (2006.01) ,A61J 1/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
36
Polysaccharides; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
J
CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
1
Containers specially adapted for medical or pharmaceutical purposes
Applicants:
EPSILON PHARMACEUTICALS LIMITED [GB/GB]; Barnston House Beacon Lane Heswall Wirral Cheshire CH60 0EE, GB
Inventors:
TICKLE, Stephen; GB
GOULD, William; GB
Agent:
BROWNE, Robin Forsythe; GB
Priority Data:
1715841.129.09.2017GB
Title (EN) CAPTOPRIL LIQUID DOSAGE FORM AND DELIVERY SYSTEM
(FR) FORME POSOLOGIQUE LIQUIDE DE CAPTOPRIL ET SYSTÈME DE DISTRIBUTION
Abstract:
(EN) A container comprising a pharmaceutical dosage form, the pharmaceutical dosage form comprising solid and liquid components; the solid component comprising: captopril as active ingredient; and at least one water soluble excipient; the liquid component comprising: water; sodium metabisulphite; at least one sequestrant; and optional further excipients; the container having two separate compartments separated by a breakable barrier, the solid component located in a first compartment and the liquid component located in a second compartment; the breakable barrier being arranged to be broken by a user to allow the solid component and the liquid component to mix to provide the dosage form for use.
(FR) L'invention concerne un récipient comprenant une forme posologique pharmaceutique, la forme posologique pharmaceutique comprenant des composants solide et liquide ; le composant solide comprenant : du captopril en tant que principe actif; et au moins un excipient soluble dans l'eau ; le composant liquide comprenant : de l'eau ; du métabisulfite de sodium ; au moins un séquestrant ; et de façon optionnelle d'autres excipients ; le récipient ayant deux compartiments séparés séparés par une barrière cassable, le composant solide étant situé dans un premier compartiment et le composant liquide étant situé dans un second compartiment ; la barrière cassable étant conçue pour être rompue par un utilisateur pour permettre au composant solide et au composant liquide de se mélanger pour fournir la forme posologique à utiliser.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)