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1. (WO2019063638) FUNCTIONALIZED POLYMERS FOR THE INTRACELLULAR RELEASE OF BIOACTIVE MOLECULES
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Pub. No.: WO/2019/063638 International Application No.: PCT/EP2018/076171
Publication Date: 04.04.2019 International Filing Date: 26.09.2018
IPC:
A61K 9/51 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
48
Preparations in capsules, e.g. of gelatin, of chocolate
50
Microcapsules
51
Nanocapsules
Applicants:
SUNYAMED S.R.L. [IT/IT]; Corso Vittorio Emanuele 203 84122 SALERNO, IT
Inventors:
PELUSO, Gianfranco; IT
Agent:
BANFI, Paolo; IT
Priority Data:
10201700010827427.09.2017IT
Title (EN) FUNCTIONALIZED POLYMERS FOR THE INTRACELLULAR RELEASE OF BIOACTIVE MOLECULES
(FR) POLYMÈRES FONCTIONNALISÉS POUR LA LIBÉRATION INTRACELLULAIRE DE MOLÉCULES BIOLOGIQUEMENT ACTIVES
Abstract:
(EN) This invention pertains to systems suitable for the intracellular release of bioactive compounds, such systems comprising a biocompatible and/or biodegradable polymer derivatized with radicals R, A, B or C described herein and their use for transporting bioactive compounds inside cells that express an organic cationic transporter, particularly SLC22A4, SLC6A14 e SLC22A16.
(FR) La présente invention concerne des systèmes appropriés pour la libération intracellulaire de composés biologiquement actifs, ces systèmes comprenant un polymère biocompatible et/ou biodégradable dérivé par des radicaux R, A, B ou C décrits dans la description et leur utilisation pour transporter des composés biologiquement actifs à l'intérieur de cellules qui expriment un transporteur cationique organique, en particulier SLC22A4, SLC6A14 et SLC22A16.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)