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1. (WO2019063101) NEW BIO-PESTICIDES FOR CONTROLLING PLANT PESTS
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Pub. No.: WO/2019/063101 International Application No.: PCT/EP2017/074877
Publication Date: 04.04.2019 International Filing Date: 29.09.2017
IPC:
C12N 15/82 (2006.01) ,A01N 25/00 (2006.01) ,A01N 27/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
82
for plant cells
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
25
Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
27
Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
Applicants:
KMETIJSKI INŠTITUT SLOVENIJE [SI/SI]; Hacquetova ulica 17 1000 Ljubljana, SI
UNIVERZA V LJUBLJANI [SI/SI]; Kongresni trg 12 1000 Ljubljana, SI
Inventors:
PANEVSKA, Anastasija; BG
RAZINGER, Jaka; SI
SEPCIC, Kristina; SI
MACEK, Peter; SI
SKOCAJ, Matej; SI
MODIC, Špela; SI
NOVAK, Maruša; SI
BUTALA, Matej; SI
HODNIK, Vesna; SI
GRUNDNER, Maja; SI
TURK, Tom; SI
Agent:
ZACCO GMBH; Bayerstrasse 83 80335 Munich, DE
Priority Data:
Title (EN) NEW BIO-PESTICIDES FOR CONTROLLING PLANT PESTS
(FR) NOUVEAUX BIOPESTICIDES POUR LUTTER CONTRE LES PARASITES DES PLANTES
Abstract:
(EN) The present invention relates to cytolytic bi-component protein complexes consisting of a plurality of molecules of a member of the aegerolysin family and a plurality of molecules of a member of the MACPF superfamily, and particularly to their use for controlling a plant pest, such as for controlling Colorado potato beetle (Leptinotarsa decemlineata) or Western corn rootworm (Diabrotica virgifera virgifera). More specifically, the invention relates to cytolytic bi-component protein complexes formed by a plurality of molecules of one of the aegerolysins ostreolysin A6 (OlyA6), pleurotolysin A2 (PlyA2) and erylysin A (EryA) with a plurality of molecules of pleurotolysin B (PlyB) or similar proteins, which have been shown to be toxic for the aforementioned agricultural pest insects.
(FR) La présente invention concerne des complexes de protéines bi-composants cytolytiques constitués d'une pluralité de molécules d'un membre de la famille des aegerolysines et d'une pluralité de molécules d'un membre de la superfamille MACPF, et en particulier leur utilisation pour lutter contre un parasite des plantes, par exemple pour lutter contre le doryphore (Leptinotarsa decemlineata) ou la chrysomèle occidentale des racines du maïs (Diabrotica virgifera virgifera). Plus spécifiquement, l'invention concerne des complexes de protéines bi-composants cytolytiques formés par une pluralité de molécules d'un élément parmi les aegerolysines ostreolysine A6 (OlyA6), pleurotolysine A2 (PlyA2) et erylysine A (EryA) avec une pluralité de molécules de pleurotolysine B (PlyB) ou de protéines similaires, qui ont été reconnues comme toxiques pour les insectes nuisibles agricoles mentionnés ci-dessus.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)