Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019062325) POLYPEPTIDE DERIVED FROM RPS23RG1 AND USES THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/062325 International Application No.: PCT/CN2018/098264
Publication Date: 04.04.2019 International Filing Date: 02.08.2018
IPC:
C07K 14/435 (2006.01) ,C12N 15/12 (2006.01) ,C12N 15/79 (2006.01) ,A61K 38/17 (2006.01) ,A61P 25/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
厦门大学 XIAMEN UNIVERSITY [CN/CN]; 中国福建省厦门市 思明区思明南路422号 No.422 Si Ming Nan Road, Siming District Xiamen, Fujian 361005, CN
Inventors:
张云武 ZHANG, Yunwu; CN
赵东栋 ZHAO, Dongdong; CN
张慕娴 ZHANG, Muxian; CN
孟健 MENG, Jian; CN
许华曦 XU, Huaxi; CN
Agent:
中国国际贸易促进委员会专利商标事务所 CCPIT PATENT AND TRADEMARK LAW OFFICE; 中国北京市 西城区阜成门外大街2号万通新世界广场8层 8th Floor, Vantone New World Plaza, 2 Fuchengmenwai Street, Xicheng District Beijing 100037, CN
Priority Data:
201710895654.928.09.2017CN
Title (EN) POLYPEPTIDE DERIVED FROM RPS23RG1 AND USES THEREOF
(FR) POLYPEPTIDE DÉRIVÉ DE RPS23RG1 ET SES UTILISATIONS
(ZH) 一种衍生自RPS23RG1的多肽及其应用
Abstract:
(EN) Provided is a specific polypeptide fragment or a variant thereof derived from a RPS23RG1 protein comprising a Thr Thr Leu Ala His fragment. Also provided are a conjugate, comprising said polypeptide fragment or a variant thereof, a fusion protein and a pharmaceutical composition, and uses thereof for preparing a drug for treating diseases related to extremely low activity of PSD-95 and/or PSD-93 .
(FR) Fait l’objet de la présente invention un fragment polypeptidique spécifique ou sa variante dérivé d’une protéine RPS23RG1 comprenant un fragment Thr Thr Leu Ala His. Fait aussi l’objet de la présente invention un conjugué comprenant ledit fragment polypeptidique ou sa variante, une protéine de fusion et une composition pharmaceutique, ledit conjugué servant à préparer un médicament pour le traitement de maladies associées à l’activité extrêmement faible de PSD-95 et/ou PSD-93.
(ZH) 提供了一种RPS23RG1蛋白的特定多肽片段或其变体,其包含Thr Thr Leu Ala His片段。还提供了包含该多肽片段或其变体的缀合物、融合蛋白、药物组合物及其用于制备治疗与PSD-95和/或PSD-93活性过低相关疾病的药物中的用途。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)