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1. (WO2019061861) APPLICATION OF GPR1 GENE IN DIAGNOSING OR TREATING DISEASE RELATED TO ABNORMAL BONE GROWTH OR OSSEOUS ABNORMALITY
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/061861 International Application No.: PCT/CN2017/116609
Publication Date: 04.04.2019 International Filing Date: 15.12.2017
IPC:
C12Q 1/68 (2018.01) ,A61K 38/17 (2006.01) ,A61P 19/10 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19
Drugs for skeletal disorders
08
for bone diseases, e.g. rachitism, Paget's disease
10
for osteoporosis
Applicants:
深圳先进技术研究院 SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY [CN/CN]; 中国广东省深圳市 南山区西丽大学城学苑大道1068号 No. 1068, Xueyuan Avenue Xili University Town, Nanshan District Shenzhen, Guangdong 518055, CN
Inventors:
张键 ZHANG, Jian; CN
向亮 XIANG, Liang; CN
李健 LI, Jian; CN
任培根 REN, Peigen; CN
Agent:
北京市诚辉律师事务所 BEIJING CHENGHUI LAW FIRM; 中国北京市 朝阳区朝阳北路99号楼2单元905 905, Tower 2, No. 99 Chaoyang North Road Chaoyang District Beijing 100123, CN
Priority Data:
201710883326.726.09.2017CN
Title (EN) APPLICATION OF GPR1 GENE IN DIAGNOSING OR TREATING DISEASE RELATED TO ABNORMAL BONE GROWTH OR OSSEOUS ABNORMALITY
(FR) APPLICATION DU GÈNE GPR1 DANS LE DIAGNOSTIC OU LE TRAITEMENT D'UNE MALADIE LIÉE À UNE CROISSANCE OSSEUSE ANORMALE OU À UNE ANOMALIE OSSEUSE
(ZH) GPR1基因在诊断或治疗骨生长或骨质异常疾病的应用
Abstract:
(EN) The present invention provides an application of GPR1 gene in diagnosing or treating a disease related to bone metabolism. In particular, the present invention provides a use of GPR1 gene or GPR1 protein as a drug target in screening and/or preparing a drug for preventing and/or treating a metabolic bone disease and a use of an agonist of GPR1 in preparing a drug for preventing and/or treating a metabolic bone disease.
(FR) L'invention concerne une application du gène GPR1 dans le diagnostic ou le traitement d'une maladie liée au métabolisme osseux. L'invention concerne en particulier l'utilisation d'un gène GPR1 ou d'une protéine du GPR1 en tant que cible médicamenteuse dans le criblage et/ou la préparation d'un médicament destiné à la prévention et/ou au traitement d'une maladie osseuse métabolique, ainsi que l'utilisation d'un agoniste de GPR1 dans la préparation d'un médicament destiné à la prévention et/ou au traitement d'une maladie osseuse métabolique.
(ZH) 本发明公开了GPR1基因在诊断或治疗骨代谢相关疾病的应用,具体公开了一种GPR1基因或GPR1蛋白作为药物靶点在筛选和/或制备预防和/或治疗骨代谢疾病药物中的用途,以及GPR1的激动剂在制备预防和/或治疗骨代谢疾病药物中的用途。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)