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1. (WO2019060962) METABOLITE INSPIRED SELECTIVE OXYTOCIN RECEPTOR AGONISTS
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Pub. No.: WO/2019/060962 International Application No.: PCT/AU2018/051062
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
C07K 7/16 (2006.01) ,A61K 38/00 (2006.01) ,A61P 25/18 (2006.01) ,A61P 25/22 (2006.01) ,A61P 25/30 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
16
Oxytocins; Vasopressins; Related peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
18
Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
22
Anxiolytics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
30
for treating abuse or dependence
Applicants:
THE UNIVERSITY OF SYDNEY [AU/AU]; Parramatta Road The University of Sydney, New South Wales 2006, AU
Inventors:
KASSIOU, Michael; AU
GULLIVER, Damien; AU
REEKIE, Tristan; AU
KATTE, Timothy; AU
JORGENSEN, William; AU
WERRY, Eryn; AU
Agent:
FPA PATENT ATTORNEYS PTY LTD; Level 43 101 Collins Street Melbourne, Victoria 3000, AU
Priority Data:
201790393528.09.2017AU
Title (EN) METABOLITE INSPIRED SELECTIVE OXYTOCIN RECEPTOR AGONISTS
(FR) AGONISTES SÉLECTIFS DU RÉCEPTEUR DE L'OCYTOCINE, INSPIRÉS DES MÉTABOLITES
Abstract:
(EN) Compound of Formula I being cyclic metabolites of oxytocin. These derivatives have enhanced selectivity for the oxytocin receptor.
(FR) La présente invention concerne un composé représenté par la formule I qui est se présente en tant que métabolites cycliques d'ocytocine. Ces dérivés présentent une sélectivité améliorée vis-à-vis du récepteur de l'ocytocine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)