Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019060960) METHOD OF PROGNOSIS
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/060960 International Application No.: PCT/AU2018/051059
Publication Date: 04.04.2019 International Filing Date: 27.09.2018
IPC:
G01N 33/68 (2006.01) ,A61K 38/49 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43
Enzymes; Proenzymes; Derivatives thereof
46
Hydrolases (3)
48
acting on peptide bonds (3.4)
49
Urokinase; Tissue plasminogen activator
Applicants:
ALFRED HEALTH [AU/AU]; 55 Commercial Road Melbourne, Victoria 3004, AU
PEKING UNIVERSITY THIRD HOSPITAL [CN/CN]; No 49 North Garden Road Haidian District Bejing, Beijing 100191, CN
Inventors:
DART, Anthony; AU
GAO, Wei; CN
Agent:
FPA PATENT ATTORNEYS PTY LTD; Level 43 101 Collins Street Melbourne, Victoria 3000, AU
Priority Data:
PCT/CN2017/10475230.09.2017CN
Title (EN) METHOD OF PROGNOSIS
(FR) MÉTHODE DE PRONOSTIC
Abstract:
(EN) The invention relates to a method for prognosing ACS in a subject, the method comprising determining plasma MIF and Nt-proBNP (or BNP) concentrations in a sample from the subject, diagnosing ACS when the subject plasma concentrations are greater than a reference MIF and Nt-proBNP (or BNP) plasma concentration, and prognosing the magnitude of ACS from the subject plasma MIF and Nt-proBNP (or BNP) concentrations. Also provided is a method of treating ACS in a subject, a device, a kit, and a cardiac biomarker related to the methods of prognosing ACS.
(FR) L'invention concerne une méthode permettant de pronostiquer un SCA chez un sujet, la méthode consistant à déterminer des concentrations de MIF et de Nt-proBNP (ou BNP) plasmatiques dans un échantillon provenant du sujet, à diagnostiquer un SCA lorsque les concentrations plasmatiques du sujet sont supérieures à une concentration plasmatique de MIF et de Nt-proBNP (ou BNP) de référence, et à pronostiquer l'importance du SCA à partir des concentrations de MIF et de Nt-proBNP (ou BNP) plasmatiques du sujet. L'invention concerne également une méthode de traitement de SCA chez un sujet, un dispositif, un kit et un biomarqueur cardiaque concernant les méthodes de pronostic de SCA.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)