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1. WO2019059661 - METHOD FOR PREPARING COSMETIC COMPOSITION HAVING BIOLOGICALLY ACTIVE SUBSTANCE DISPERSED THEREIN

Publication Number WO/2019/059661
Publication Date 28.03.2019
International Application No. PCT/KR2018/011101
International Filing Date 20.09.2018
IPC
A61K 8/35 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
35Ketones, e.g. quinones, benzophenone
A61K 8/31 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
31Hydrocarbons
A61K 8/19 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
CPC
A61K 2800/33
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
20Chemical, physico-chemical or functional or structural properties of the composition as a whole
30Characterized by the absence of a particular group of ingredients
33Free of surfactant
A61K 2800/413
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
41Particular ingredients further characterized by their size
413Nanosized, i.e. having sizes below 100 nm
A61K 8/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
19containing inorganic ingredients
A61K 8/31
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
31Hydrocarbons
A61K 8/355
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
35Ketones, e.g. benzophenone
355Quinones
A61Q 19/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
Applicants
  • 나노다이아랩 주식회사 NANODIALAB CO.,LTD [KR]/[KR]
  • 나노리소스 주식회사 NANORESOURCE CO.,LTD [KR]/[KR]
Inventors
  • 권명택 KWON, Myoungtaek
  • 임선희 LIM, Sunhee
  • 양지혁 YANG, Jihyek
Agents
  • 이준혁 LEE, Junhyek
Priority Data
10-2017-012231722.09.2017KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PREPARING COSMETIC COMPOSITION HAVING BIOLOGICALLY ACTIVE SUBSTANCE DISPERSED THEREIN
(FR) PROCÉDÉ DE PRÉPARATION D’UNE COMPOSITION COSMÉTIQUE COMPORTANT UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE DISPERSÉE DANS CELLE-CI
(KO) 생리활성물질이 분산된 화장료 조성물의 제조방법
Abstract
(EN)
The present invention relates to a carotenoid-containing nano-diamond composition having dispersibility, uniformity, and stability by allowing poorly water-soluble carotenoid to be adsorbed onto surfaces of nano-diamonds dispersed in a hydrophilic solvent. The present invention provides a composition wherein carotenoid (astaxanthin), which is insoluble in water and present in aggregate, is adsorbed onto nanodiamonds to increase dispersibility thereof in a hydrophilic solvent, such as water. In the composition containing carotenoid (astaxanthin) and nanodiamonds of the present invention, carotenoid (astaxanthin) is adsorbed onto nanodiamonds, and thus carotenoid can be present in the composition for a long time without being easily denatured by heat, oxygen, or light. That is, when the composition of the present invention is used as a cosmetic material, a surfactant is not used, or even if the surfactant is used, the use amount thereof can be decreased, and therefore, a skin-friendly natural cosmetic material can be provided. The cosmetic composition of the present invention allows carotenoid (astaxanthin) to be stably dispersed and maintained for a long time, and therefore, can exhibit inherent functions and color (antioxidative characteristics and red color) of carotenoid (astaxanthin) for a long time.
(FR)
La présente invention concerne une composition de nanodiamant contenant un caroténoïde présentant une dispersibilité, une uniformité et une stabilité en permettant à un caroténoïde faiblement soluble dans l’eau d’être adsorbé sur des surfaces de nanodiamants dispersés dans un solvant hydrophile. La présente invention concerne une composition dans laquelle un caroténoïde (astaxanthine), qui est insoluble dans l’eau et présent dans un agrégat, est adsorbé sur des nanodiamants pour augmenter la dispersibilité de celui-ci dans un solvant hydrophile, tel que l’eau. Dans la composition contenant un caroténoïde (astaxanthine) et des nanodiamants de la présente invention, le caroténoïde (astaxanthine) est adsorbé sur des nanodiamants et, par conséquent, le caroténoïde peut être présent dans la composition pendant une longue durée sans être facilement dénaturé par la chaleur, l’oxygène ou la lumière. À savoir, lorsque la composition de la présente invention est utilisée en tant que matériau cosmétique, un tensioactif n’est pas utilisé, ou même si le tensioactif est utilisé, la quantité d’utilisation de celui-ci peut être diminuée et, par conséquent, un matériau cosmétique naturel respectueux de la peau peut être fourni. La composition cosmétique de la présente invention permet qu’un caroténoïde (astaxanthine) qoit dispersé et maintenu de façon stable pendant une longue durée et, par conséquent, peut présenter des fonctions et une couleur inhérentes (caractéristiques antioxydantes et couleur rouge) du caroténoïde (astaxanthine) pendant une longue durée.
(KO)
본 발명은 친수성 용매에 분산된 나노다이아몬드 표면에 물에 난용성인 카로티노이드를 흡착시켜 분산성, 균일성 및 안정성을 가지는 카로티노이드 함유 나노다이아몬드 조성물에 관한 것이다. 본 발명은 물에 불용성이며 응집되어 존재하는 카로티노이드(아스타잔틴)를 나노다이아몬드에 흡착시켜 물 등 친수성 용매에 분산성을 높인 조성물을 제공한다. 본 발명의 카로티노이드(아스타잔틴)와 나노다이아몬드 함유 조성물은 카로티노이드(아스타잔틴)가 나노다이아몬드에 흡착됨에 따라 열, 산소나 빛에 쉽게 변성되지 않고 장시간 동안 조성물 내에 존재할 수 있다. 즉, 본 발명의 조성물은 화장료로 사용되는 경우에 계면활성제를 사용하지 않거나 사용하더라도 사용량을 줄일 수 있으므로 피부 친화적인 천연 화장료를 제공할 수 있다. 본 발명의 화장료 조성물은 카로티노이드(아스타잔틴)를 안정적으로 장기간 분산 유지시키므로, 카로티노이드(아스타잔틴)의 고유 기능과 색(항산화 특성과 적색)을 오랫동안 발휘할 수 있다.
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