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1. WO2019055590 - BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/US2018/050793 01017/40079/PC
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
13 September 2018 13 September 2017
Applicant
AMGEN INC.
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C07D 403/12 (2006.01)i; C07D 401/14 (2006.01)i; C07D 413/14 (2006.01)i; C07D 401/06 (2006.01)i; C07D 403/14 (2006.01)i; C07D 405/12 (2006.01)i; C07D 413/12 (2006.01)i; C07D 417/14 (2006.01)i; C07D 207/16 (2006.01)i; C07D 209/02 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C07D
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, CHEM ABS Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
A
US 2009192168 A1 (MUCI ALEX [US] ET AL) 30 July 2009 (2009-07-30)
1-35
the whole document
(2)
A
US 2007078126 A1 (MORGAN BRADLEY P [US] ET AL) 05 April 2007 (2007-04-05)
1-35
the whole document
(3)
X
US 2014356322 A1 (CREWS CRAIG M [US] ET AL) 04 December 2014 (2014-12-04)
1
Compounds VL064, VL096-VL98, VL124-VL130, VL203;claim 149
(4)
X
GUYLAINE CUNY ET AL, "Palladium- and Copper-Catalyzed Synthesis of Medium- and Large-Sized Ring-Fused Dihydroazaphenanthrenes and 1,4-Benzodiazepine-2,5-diones. Control of Reaction Pathway by Metal-Switching", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,Vol. 126, No. 44, 01 November 2004 (2004-11-01), page 14475-14484,
XP055521669
1
compounds 3a,3b,3d,3f,3g
(5)
X
US 4904680 A (MATSUI TAKASHI [JP] ET AL) 27 February 1990 (1990-02-27)
1
claim 1; compounds 97,98101,102,115-119,125,133,136
(6)
X
PubChem online05 December 2007 (2007-12-05), retrieved from NCBIDatabase accession no. 20954608
XP002786306
1
compound 20954608
(7)
X
PubChem online25 October 2006 (2006-10-25), retrieved from NCBIDatabase accession no. 9893412
XP002786307
1
compound 9893412
(8)
X
PubChem online26 October 2006 (2006-10-26), retrieved from NCBIDatabase accession no. 10984090
XP002786308
1
compound 10984090
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
US 2009192168 A1
30 July 2009
NONE
US 2007078126 A1
05 April 2007
AT 524452 T
EP 1605752 A1
ES 2378620 T3
JP 4969238 B2
JP 2006523234 A
JP 2012092135 A
US 2007078126 A1
US 2010069370 A1
US 2011112154 A1
US 2012088779 A1
US 2012232092 A1
US 2013267537 A1
WO 2004086865 A1
15 September 2011
21 December 2005
16 April 2012
04 July 2012
12 October 2006
17 May 2012
05 April 2007
18 March 2010
12 May 2011
12 April 2012
13 September 2012
10 October 2013
14 October 2004
US 2014356322 A1
04 December 2014
AU 2013207900 A1
AU 2018201554 A1
BR 112014017095 A2
CA 2861066 A1
CN 104736569 A
EP 2802608 A2
HK 1208875 A1
JP 2015508414 A
KR 20150010935 A
RU 2014133019 A
US 2014356322 A1
WO 2013106643 A2
24 July 2014
29 March 2018
13 June 2017
18 July 2013
24 June 2015
19 November 2014
18 March 2016
19 March 2015
29 January 2015
27 February 2016
04 December 2014
18 July 2013
US 4904680 A
27 February 1990
CA 1283917 C
DE 3575554 D1
EP 0173441 A1
ES 8703830 A1
ES 8801185 A1
ES 8801186 A1
JP H0662529 B2
JP S6124550 A
US 4904680 A
07 May 1991
01 March 1990
05 March 1986
01 March 1987
01 January 1988
01 January 1988
17 August 1994
03 February 1986
27 February 1990
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
07 November 2018
Date of mailing of the international search report:
30 November 2018
Authorized officer:
Grassi, Damian
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