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1. WO2019054970 - METHOD OF PRODUCING PLGA FIBERS USED AS TISSUE SCAFFOLDS AND THE PLGA FIBERS PRODUCED WITH THIS METHOD

Publication Number WO/2019/054970
Publication Date 21.03.2019
International Application No. PCT/TR2018/050482
International Filing Date 12.09.2018
IPC
D01D 5/06 2006.01
DTEXTILES; PAPER
01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF MAN-MADE FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
5Formation of filaments, threads, or the like
06Wet spinning methods
D01D 5/00 2006.01
DTEXTILES; PAPER
01NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
DMECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF MAN-MADE FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
5Formation of filaments, threads, or the like
A61L 27/18 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
14Macromolecular materials
18obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A61K 47/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
C12N 5/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
CPC
A61K 47/34
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61L 27/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
14Macromolecular materials
18obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
A61L 27/56
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
56Porous materials, ; e.g. foams or sponges
A61L 27/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
50Materials characterised by their function or physical properties ; , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
58Materials at least partially resorbable by the body
Applicants
  • YEDITEPE UNIVERSITESI [TR]/[TR]
Inventors
  • GÜREL PEKÖZER, Görke
  • ABAY, Nergis
  • TORUN KOSE, Gamze
Agents
  • ANKARA PATENT BUREAU
Priority Data
2017/1347013.09.2017TR
Publication Language English (EN)
Filing Language Turkish (TR)
Designated States
Title
(EN) METHOD OF PRODUCING PLGA FIBERS USED AS TISSUE SCAFFOLDS AND THE PLGA FIBERS PRODUCED WITH THIS METHOD
(FR) MÉTHODE DE PRODUCTION DE FIBRES PLGA UTILISÉES COMME ÉCHAFAUDAGE TISSULAIRE ET LES FIBRES PLGA PRODUITES SELON CETTE MÉTHODE
Abstract
(EN)
The present invention relates to the production of PLGA (poly(lactic-co-glycolic acid)) fibers obtained by wet spinning method from PLGA polymer be used as tissue engineering scaffolds for repair of critical size bone defects. The objective of the invention is to provide PLGA fibers having a fibrous structure by wet spinning method that can provide long-term mechanical support and low biodegradation rate.
(FR)
La présente invention concerne la production de fibres PLGA (acide poly(lactic-co-glycolique)) obtenues par une méthode de filage par voie humide à partir du polymère PLGA, et utilisés comme échafaudages de génie tissulaire pour la réparation de défauts osseux de taille critique. L'invention vise à fournir des fibres PLGA ayant une structure fibreuse par une méthode de filage par voie humide et permettant de fournir un support mécanique à long terme et un faible taux de biodégradation.
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