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1. WO2019053247 - MANUFACTURING OF PHARMACEUTICAL COMPOSITIONS

Publication Number WO/2019/053247
Publication Date 21.03.2019
International Application No. PCT/EP2018/075034
International Filing Date 17.09.2018
IPC
A61K 9/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
A61K 38/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
B01F 15/00 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
15Accessories for mixers
CPC
A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
B01F 2101/22
B01F 23/024
B01F 23/062
B01F 27/1143
B01F 27/72
Applicants
  • FERRING INTERNATIONAL CENTER S.A. [CH]/[CH]
Inventors
  • RÖNNBACK, Robert
  • SAUNIER, Josselin
Agents
  • BRUNETTI, Fabrizio
  • DEN HARTOG, Jeroen
  • DERKS, Wilhelmus
  • OWEN, David
  • PIERCE, Christopher
  • AMIRSEHHI, Ramin
  • LIN, Hsueh-Yen
  • ELKENBRACHT, Johan
  • HAARTSEN, Jan Pieter
  • PFISTER, Matthias
  • DE BAAT, Michiel Anton
  • TSAI, Philip
Priority Data
17191652.118.09.2017EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) MANUFACTURING OF PHARMACEUTICAL COMPOSITIONS
(FR) FABRICATION DE COMPOSITIONS PHARMACEUTIQUES
Abstract
(EN) The present disclosure discloses a process for the continuous manufacture of a liquid pharmaceutical composition, the process comprising providing a mixing unit, feeding a therapeutic agent and a liquid vehicle to the mixing unit, operating the latter thereby mixing the agent and the vehicle into a liquid pharmaceutical composition, discharging the composition into a holding unit.
(FR) La présente invention concerne un procédé de fabrication en continu d'une composition pharmaceutique liquide, le procédé comprenant l'utilisation d'un mélangeur, l'introduction d'un agent thérapeutique et d'un excipient liquide dans le mélangeur, l'actionnement de ce dernier afin de mélanger l'agent et l'excipient pour former une composition pharmaceutique liquide et l'évacuation de la composition en direction d'une unité de stockage.
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