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1. (WO2019050775) PRIDOPIDINE FOR TREATING DRUG INDUCED DYSKINESIAS
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Pub. No.: WO/2019/050775 International Application No.: PCT/US2018/048920
Publication Date: 14.03.2019 International Filing Date: 30.08.2018
IPC:
A61K 31/451 (2006.01) ,A61K 45/06 (2006.01) ,A61P 25/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
451
having a carbocyclic ring directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
14
for treating abnormal movements, e.g. chorea, dyskinesia
Applicants:
GEVA, Michal [IL/IL]; IL (US)
ORBACH, Aric [IL/IL]; IL (US)
HAYDEN, Michael [IL/IL]; IL (US)
PRILENIA THERAPEUTICS DEVELOPMENT LTD. [IL/IL]; HaMenofim 10 Street Herzliya 4672561, IL (AllExceptUS)
TEVA PHARMACEUTICALS USA, INC. [US/US]; 1090 Horsham Road North Wales, PA 19454, US (BB)
Inventors:
GEVA, Michal; IL
ORBACH, Aric; IL
HAYDEN, Michael; IL
Agent:
COHEN, Mark, S.; US
Priority Data:
62/556,31408.09.2017US
62/649,18428.03.2018US
Title (EN) PRIDOPIDINE FOR TREATING DRUG INDUCED DYSKINESIAS
(FR) PRIDOPIDINE POUR LE TRAITEMENT DE DYSKINÉSIES INDUITES PAR UN MÉDICAMENT
Abstract:
(EN) The invention provides a method of treating a subject afflicted with a drug-induced movement disorder including levodopa-induced dyskinesia comprising periodically administering to the subject in need thereof an amount of pridopidine effective to treat the subject. The invention further provides a method of treating a subject at risk of developing a drug-induced movement disorder, including levodopa-induced dyskinesia. The invention also provides pharmaceutical compositions suitable for carrying out these methods and packages containing such pharmaceutical compositions.
(FR) L'invention concerne une méthode de traitement d'un sujet atteint d'un trouble de mouvement induit par un médicament comprenant la dyskinésie induite par la lévodopa, comprenant l'administration périodique au sujet en ayant besoin d'une quantité de pridopidine efficace pour traiter le sujet. L'invention concerne en outre une méthode de traitement d'un sujet présentant un risque de développer un trouble de mouvement induit par un médicament, y compris la dyskinésie induite par la lévodopa. L'invention concerne également des compositions pharmaceutiques appropriées pour la mise en œuvre de ces méthodes et des emballages contenant de telles compositions pharmaceutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)