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1. (WO2019050350) STEM CELL-DERIVED SERTOLI-LIKE CELL, PREPARATION METHOD THEREFOR, AND USE THEREOF
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Pub. No.: WO/2019/050350 International Application No.: PCT/KR2018/010525
Publication Date: 14.03.2019 International Filing Date: 07.09.2018
IPC:
C12N 5/071 (2010.01) ,A61K 35/52 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07
Animal cells or tissues
071
Vertebrate cells or tissues, e.g. human cells or tissues
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
12
Materials from mammals or birds
48
Reproductive organs; Embryos
52
Sperm
Applicants:
차의과학대학교 산학협력단 CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR/KR]; 경기도 포천시 해룡로 120 120, Haeryong-ro, Pocheon-si, Gyeonggi-do 11160, KR
Inventors:
이동율 LEE, Dong Ryul; KR
설동원 SEOL, Dong Won; KR
Agent:
리앤목 특허법인 Y.P.LEE, MOCK & PARTNERS; 서울시 강남구 언주로 30길 13 대림아크로텔 12층 12F Daelim Acrotel, 13 Eonju-ro 30-gil Gangnam-gu, Seoul 06292, KR
Priority Data:
10-2017-011468007.09.2017KR
Title (EN) STEM CELL-DERIVED SERTOLI-LIKE CELL, PREPARATION METHOD THEREFOR, AND USE THEREOF
(FR) CELLULE DE TYPE DE SERTOLI DÉRIVÉE DE CELLULE SOUCHE PROCÉDÉ DE PRÉPARATION ASSOCIÉ ET UTILISATION ASSOCIÉE
(KO) 줄기세포 유래 세르톨리유사세포, 그 제조방법, 및 그의 용도
Abstract:
(EN) The present invention relates to a stem cell-derived Sertoli-like cell, a preparation method therefor, and a use thereof. According to one embodiment, Sertoli-like cells can be obtained on mass scale because of the differentiation thereof from embryonic stem cells, which are highly proliferative, and can be used in developing a cell therapy product because the cells can secrete an immunosuppressive material to establish immune privilege and induce an anti-inflammatory function.
(FR) La présente invention concerne une cellule de type de Sertoli dérivée d'une cellule souche, un procédé de préparation associé et une utilisation associée. Selon un mode de réalisation, des cellules de type de Sertoli peuvent être obtenues à grande échelle en raison de leur différenciation à partir de cellules souches embryonnaires, qui sont hautement prolifératives, et peuvent être utilisées dans le développement d'un produit de thérapie cellulaire étant donné que les cellules peuvent sécréter un matériau immunosuppresseur pour établir un privilège immunitaire et induire une fonction anti-inflammatoire.
(KO) 줄기세포 유래 세로톨리유사세포, 그 제조방법, 및 그 용도에 관한 것이다. 일 구체예에 따른 세르톨리유사세포는 증식력이 우수한 배아줄기세포로부터 분화시킬 수 있으므로 대량으로 확보가 가능하며, 면역억제물질을 분비하여 면역특권을 형성하고 항염증 기능을 유도할 수 있기 때문에 세포치료제 개발에 활용할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)