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1. (WO2019049991) CYTOCHROME P450 MONOOXYGENASE DECOY SUBSTRATE
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Pub. No.: WO/2019/049991 International Application No.: PCT/JP2018/033217
Publication Date: 14.03.2019 International Filing Date: 07.09.2018
IPC:
C07K 5/078 (2006.01) ,C12P 1/00 (2006.01) ,C12P 7/02 (2006.01) ,C12N 15/53 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
06
Dipeptides
078
the first amino acid being heterocyclic, e.g. Pro, His, Trp
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
1
Preparation of compounds or compositions, not provided for in groups C12P3/-C12P39/121; General processes for the preparation of compounds or compositions by using micro-organisms or enzymes
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7
Preparation of oxygen-containing organic compounds
02
containing a hydroxy group
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
52
Genes encoding for enzymes or proenzymes
53
Oxidoreductases (1)
Applicants:
国立大学法人名古屋大学 NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY [JP/JP]; 愛知県名古屋市千種区不老町1番 1, Furo-cho, Chikusa-ku, Nagoya-shi, Aichi 4648601, JP
Inventors:
渡辺 芳人 WATANABE, Yoshihito; JP
荘司 長三 SHOJI, Osami; JP
Agent:
特許業務法人三枝国際特許事務所 SAEGUSA & PARTNERS; 大阪府大阪市中央区道修町1-7-1 北浜TNKビル Kitahama TNK Building, 1-7-1, Doshomachi, Chuo-ku, Osaka-shi, Osaka 5410045, JP
Priority Data:
2017-17344608.09.2017JP
Title (EN) CYTOCHROME P450 MONOOXYGENASE DECOY SUBSTRATE
(FR) SUBSTRAT DE LEURRE DE CYTOCHROME P450 MONOOXYGÉNASE
(JA) シトクロムP450モノオキシゲナーゼデコイ基質
Abstract:
(EN) The present invention addresses the problem of providing a simpler and more efficient hydroxyhydrocarbon production technique using a cytochrome P450 monooxygenase decoy substrate, and provides: a cytochrome P450 monooxygenase decoy substrate which includes a compound represented by general formula (1) and can be used for the production of a hydroxyhydrocarbon in a cell; and a method for producing a hydroxyhydrocarbon in a cell using the cytochrome P450 monooxygenase decoy substrate.
(FR) La présente invention aborde le problème consistant à fournir une technique plus simple et plus efficace de production d'hydroxyhydrocarbures à l'aide d'un substrat de leurre de cytochrome P450 monooxygénase, et fournit : un substrat de leurre de cytochrome P450 monooxygénase comprenant un composé représenté par la formule générale (1) et peut être utilisé pour la production d'un hydroxyhydrocarbure dans une cellule ; l'invention concerne également un procédé de production d'un hydroxyhydrocarbure dans une cellule à l'aide du substrat de leurre de cytochrome P450 monooxygénase.
(JA) シトクロムP450モノオキシゲナーゼデコイ基質を用いた、より簡便且つ効率的なヒドロキシ炭化水素製造技術を提供することを課題とし、一般式(1)で表される化合物からなる、細胞内でヒドロキシ炭化水素を製造するために用いられるシトクロムP450モノオキシゲナーゼデコイ基質、及びこれを用いて細胞内でヒドロキシ炭化水素を製造する方法を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)