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1. (WO2019049829) PROGNOSTIC BIOMARKER FOR COLON CANCER
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/049829 International Application No.: PCT/JP2018/032628
Publication Date: 14.03.2019 International Filing Date: 03.09.2018
IPC:
G01N 33/68 (2006.01) ,C12N 9/10 (2006.01) ,C12N 15/54 (2006.01) ,C12N 15/65 (2006.01) ,C12Q 1/6804 (2018.01) ,C12Q 1/6813 (2018.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68
involving proteins, peptides or amino acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
52
Genes encoding for enzymes or proenzymes
54
Transferases (2)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
65
using markers
[IPC code unknown for C12Q 1/6804][IPC code unknown for C12Q 1/6813]
Applicants:
公立大学法人福島県立医科大学 FUKUSHIMA MEDICAL UNIVERSITY [JP/JP]; 福島県福島市光が丘1番地 1, Hikarigaoka, Fukushima-shi, Fukushima 9601295, JP
Inventors:
岡山 洋和 OKAYAMA Hirokazu; JP
野田 勝 NODA Masaru; JP
河野 浩二 KONO Koji; JP
Agent:
特許業務法人平木国際特許事務所 HIRAKI & ASSOCIATES; 東京都港区愛宕二丁目5-1 愛宕グリーンヒルズMORIタワー32階 Atago Green Hills MORI Tower 32F, 5-1, Atago 2-chome, Minato-ku, Tokyo 1056232, JP
Priority Data:
2017-17015705.09.2017JP
Title (EN) PROGNOSTIC BIOMARKER FOR COLON CANCER
(FR) BIOMARQUEUR DE PRONOSTIC DE CANCER DU CÔLON
(JA) 大腸がんの予後バイオマーカー
Abstract:
(EN) Provided is a biomarker for predicting the prognosis of a colon cancer patient, and/or for determining the efficacy of an anticancer agent in a colon cancer patient. Provided is a biomarker for predicting the prognosis of a colon cancer patient and/or for determining the efficacy of an anticancer agent in a colon cancer patient, the biomarker comprising a GALNT6 protein or peptide fragment thereof, or a GALNT6 gene transcription product or a nucleic acid fragment thereof.
(FR) L'invention concerne un biomarqueur permettant de prédire le pronostic d'un patient atteint d'un cancer du côlon, et/ou de déterminer l'efficacité d'un agent anticancéreux chez un patient atteint d'un cancer du côlon. L'invention concerne un biomarqueur permettant de prédire le pronostic d'un patient atteint d'un cancer du côlon et/ou de déterminer l'efficacité d'un agent anticancéreux chez un patient atteint d'un cancer du côlon, le biomarqueur comprenant une protéine GALNT6 ou un fragment peptidique de cette dernière, ou un produit de transcription de gène GALNT6 ou un fragment d'acide nucléique de ce dernier.
(JA) 大腸がん患者の予後を予測するための、及び/又は大腸がん患者に対する抗がん剤の有効性を判定するためのバイオマーカーを提供する。 GALNT6タンパク質若しくはそのペプチド断片、又はGALNT6遺伝子の転写産物若しくはその核酸断片からなる、大腸がん患者の予後を予測するための、及び/又は大腸がん患者に対する抗がん剤の有効性を判定するためのバイオマーカーを提供する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)