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1. (WO2019049186) PROCESS FOR PREPARING NANOLIPOSOMES COMPRISING MICRONUTRIENTS AND FOOD PRODUCTS COMPRISING SAID NANOLIPOSOMES
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Pub. No.: WO/2019/049186 International Application No.: PCT/IT2018/050165
Publication Date: 14.03.2019 International Filing Date: 06.09.2018
IPC:
A61K 9/127 (2006.01) ,A23L 33/16 (2016.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
127
Liposomes
[IPC code unknown for A23L 33/16]
Applicants:
ENG4LIFE S.R.L. [IT/IT]; VIA FIORENTINO, 32 83100 Avellino, IT
Inventors:
BARBA, Anna Angela; IT
LAMBERTI, Gaetano; IT
D'AMORE, Matteo; IT
BOCHICCIO, Sabrina; IT
DALMORO, Annalisa; IT
Agent:
BANCHETTI, Marina; IT
GITTO, Serena; IT
SANTI, Filippo; IT
TIBURZI, Andrea; IT
BALZANO, Francesca; IT
MULAS, Chiara; IT
FERRIERO, Paolo; IT
BIONDINI, Daniele; IT
CATALDI, Silvia; IT
Priority Data:
10201700009962706.09.2017IT
Title (EN) PROCESS FOR PREPARING NANOLIPOSOMES COMPRISING MICRONUTRIENTS AND FOOD PRODUCTS COMPRISING SAID NANOLIPOSOMES
(FR) PROCÉDÉ DE PRÉPARATION DE NANOLIPOSOMES COMPRENANT DES MICRONUTRIMENTS ET PRODUITS ALIMENTAIRES COMPRENANT LESDITS NANOLIPOSOMES
Abstract:
(EN) The invention relates to a continuous or semi-continuous, high productivity process for obtaining nanoliposomes containing iron (ll) combined with a reducing agent capable of increasing the stability and bioavailability of iron (ll), such as ascorbic acid or a salt thereof, which process is based on a high productivity "simil-microfluidic" technique for nanoliposome formation, coupled with an ultrasound treatment for the homogenization of the nanoliposomes obtained. The invention also concerns the nanoliposomes obtained by means of the described process, and the food and nutraceutical products enriched with iron(ll), in which enrichment is accomplished by using said nanoliposomes as a source of bioavailable iron.
(FR) L'invention concerne un procédé continu ou semi-continu à productivité élevée permettant d'obtenir des nanoliposomes contenant du fer (ll) combiné à un agent réducteur susceptible d'augmenter la stabilité et la biodisponibilité du fer (ll), tel que l'acide ascorbique ou un sel de celui-ci, lequel procédé est basé sur une technique « de type simil-microfluidique » à productivité élevée pour la formation de nanoliposomes, combinée à un traitement par ultrasons pour l'homogénéisation des nanoliposomes obtenus. L'invention concerne également les nanoliposomes obtenus au moyen du procédé décrit, et les produits alimentaires et nutraceutiques enrichis en fer (ll), dans lesquels l'enrichissement est réalisé en utilisant lesdits nanoliposomes en tant que source de fer biodisponible.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: Italian (IT)