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1. (WO2019049142) COMPOSITIONS COMPRISING A CANNABINOID AND SPILANTHOL
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Pub. No.: WO/2019/049142 International Application No.: PCT/IL2018/051000
Publication Date: 14.03.2019 International Filing Date: 06.09.2018
IPC:
A61K 31/352 (2006.01) ,A61K 36/28 (2006.01) ,A61P 1/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
35
having six-membered rings with one oxygen as the only ring hetero atom
352
condensed with carbocyclic rings, e.g. cannabinols, methantheline
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
185
Magnoliopsida (dicotyledons)
28
Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
Applicants:
SCICANN THERAPEUTICS INC. [CA/CA]; 69 Yonge St. Suite 1010 Toronto, ontario M5E 1K3, CA
MARK FRIEDMAN LTD. [IL/IL]; Moshe Aviv Tower 54th Floor 7 Jabotinski St. 5252007 Ramat- Gan, IL (BW)
Inventors:
KOREN, Zohar; IL
Agent:
FRIEDMAN, Mark; IL
Priority Data:
62/555,75208.09.2017US
62/591,78429.11.2017US
Title (EN) COMPOSITIONS COMPRISING A CANNABINOID AND SPILANTHOL
(FR) COMPOSITIONS COMPRENANT UN CANNABINOÏDE ET DU SPILANTHOL
Abstract:
(EN) Provided herein are fixed-dose combination (FDC) compositions comprising therapeutically effective amounts of at least one cannabinoid and spilanthol whether as essentially pure isolates or synthetics or as components of essential oils or plant extracts or combinations thereof. The compositions are formulated as pharmaceutical compositions, nutraceuticals, cosmeceuticals, nutricosmetics, cosmetics, or food products. The pharmaceutical compositions are useful for the treatment of a gastro- enteric disease selected from the group consisting of irritable bowel disease, Crohn's disease, colitis, irritable bowel syndrome, and acute and chronic pancreatitis or of sepsis. Other pharmaceutical uses are as anti-allergic, anti- inflammatory, immunomodulator, antioxidant, anti-microbial, antibacterial, antifungal, antiviral, antinociceptive, analgesic, anesthetic, anti-cancer, apoptosis inducing, antiscorbutic, antipyretic, anti-malarial, addiction mitigatory, anxiolytic, anti-depressant, diuretic, anti-diarrheal, vasodilator or aphrodisiac agents. The pharmaceutical compositions of this invention exhibit a synergistic effect.
(FR) La présente invention concerne des compositions de combinaison à dose fixe (FDC) comprenant des quantités thérapeutiquement efficaces d'au moins un cannabinoïde et de spilanthol en tant qu'isolats ou produits synthétiques sensiblement purs ou en tant que constituants d'huiles essentielles ou d'extraits végétaux ou des combinaisons de ceux-ci. Les compositions sont formulées sous la forme de compositions pharmaceutiques, de produits nutraceutiques, cosméceutiques, nutricosmétiques, cosmétiques ou alimentaires. Les compositions pharmaceutiques sont utiles pour le traitement d'une maladie gastro-entérique choisie dans le groupe constitué par la maladie du côlon irritable, la maladie de Crohn, la colite, le syndrome du côlon irritable et la pancréatite aiguë et chronique, ou d'une sepsie. D'autres utilisations pharmaceutiques existent en tant qu'agent antiallergique, anti-inflammatoire, immunomodulateur, antioxydant, antimicrobien, antibactérien, antifongique, antiviral, antinociceptif, analgésique, anesthésique, anticancéreux, inducteur d'apoptose, antiscorbutique, antipyrétique, antipaludéen, atténuateur d'addictions, anxiolytique, antidépressif, diurétique, antidiarrhéique, vasodilatateur ou aphrodisiaque. Les compositions pharmaceutiques de la présente invention présentent un effet synergique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)