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1. (WO2019049103) ORAL COMPOSITIONS, METHODS AND USES THEREOF
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Pub. No.: WO/2019/049103 International Application No.: PCT/IB2018/056930
Publication Date: 14.03.2019 International Filing Date: 11.09.2018
IPC:
A61K 9/16 (2006.01) ,A61K 9/70 (2006.01) ,A61K 31/522 (2006.01) ,A61P 43/00 (2006.01) ,A61K 9/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
70
Web, sheet or filament bases
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
52
Purines, e.g. adenine
522
having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
Applicants:
UNIVERSIDADE CATÓLICA PORTUGUESA [PT/PT]; Escola Superior De Biotecnologia, Rua Dr. António Bernardino De Almeida, 4200-072 Porto, PT
Inventors:
ESTEVEZ PINTADO, Maria Manuela; PT
NEVES MIRANDA DE CASTRO, Pedro João; PT
Agent:
TEIXEIRA DE CARVALHO, Anabela; PT
Priority Data:
11028511.09.2017PT
Title (EN) ORAL COMPOSITIONS, METHODS AND USES THEREOF
(FR) COMPOSITIONS ORALES, PROCÉDÉS ASSOCIÉS ET UTILISATIONS CORRESPONDANTES
Abstract:
(EN) The present disclosure relates to an oral composition for the controlled release of caffeine over time, products, method of obtaining and uses thereof. In view of the drawbacks to the prior art, the technical problem underlying the invention was to develop an energized oral composition that ovoid side, in particular caffeine side effects. Surprisingly, it was achieved an oral composition comprising guar-gum as a polymer, caffeine and alginate wherein 1.5 - 10% (wt/wt of dry weight of the film) of guar-gum and 10 - 30% (wt/wt of dry weight of the film) of caffeine are in a film, 10 - 25% (wt/wt of dry weight of beads) of caffeine and 1 - 5% (wt/wt of dry weight of beads) of alginate are in beads.
(FR) La présente invention concerne une composition orale pour la libération contrôlée de caféine dans le temps, des produits, un procédé d'obtention et des utilisations de celle-ci. Compte tenu des inconvénients de l'état de la technique, le problème technique sous-jacent à l'invention était de développer une composition orale énergisée qui empêche les effets secondaires, en particulier les effets secondaires de la caféine. De manière surprenante, on a obtenu une composition orale comprenant de la gomme de guar en tant que polymère, de la caféine et de l'alginate, de 1,5 à 10 % (en poids/poids de poids sec du film) de gomme de guar et de 10 à 30 % (en poids/poids de poids sec du film) de caféine se trouvant dans un film, de 10 à 25 % (en poids/poids sec de billes) de caféine et de 1 à 5 % (en poids/poids sec de billes) d'alginate étant dans des billes.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)