Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019048488) PERFORMANCE-ENHANCED PROTEASE VARIANTS III
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/048488 International Application No.: PCT/EP2018/073882
Publication Date: 14.03.2019 International Filing Date: 05.09.2018
IPC:
C12N 9/54 (2006.01) ,C11D 3/386 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
48
acting on peptide bonds, e.g. thromboplastin, leucine aminopeptidase (3.4)
50
Proteinases
52
derived from bacteria
54
bacteria being Bacillus
C CHEMISTRY; METALLURGY
11
ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
D
DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
3
Other compounding ingredients of detergent compositions covered in group C11D1/101
16
Organic compounds
38
Products with no well-defined composition
386
Preparations containing enzymes
Applicants:
HENKEL AG & CO. KGAA [DE/DE]; Henkelstrasse 67 40589 Düsseldorf, DE
Inventors:
MUSSMANN, Nina; DE
WIELAND, Susanne; DE
HERBST, Daniela; DE
PRUESER, Inken; DE
Priority Data:
10 2017 215 629.505.09.2017DE
Title (EN) PERFORMANCE-ENHANCED PROTEASE VARIANTS III
(FR) VARIANTES DE PROTÉASE À PERFORMANCES AMÉLIORÉES
(DE) LEISTUNGSVERBESSERTE PROTEASEVARIANTEN III
Abstract:
(EN) The invention relates to proteases comprising an amino acid sequence which has at least 70 % sequence identity to the amino acid sequence given in SEQ ID No.1 over its entire length, and (a) amino acid substitutions N130D on the positions corresponding to the position 30 relating to the numbering according to SEQ ID No. 1, and (b) an amino acid substitution on at least one of the positions corresponding to the positions 101, 133, 144, 224, 252 or 271, relating in each case to the numbering according to SEQ ID No.1. The invention also relates to the production and use thereof. Said type of proteases have a very good cleaning performance.
(FR) L'invention concerne des protéases comprenant une séquence d'acides aminés présentant sur sa longueur totale au moins 70 % d’identité de séquence avec la séquence d'acides aminés indiquée dans SEQ ID NO:1 et présentant (a) la substitution d'acides aminés N130D à la position qui correspond à la position 30 par rapport à la numérotation selon SEQ ID NO : 1, et (b) une substitution d'acides aminés à au moins une des positions correspondant aux positions 101, 133, 144, 224, 252 ou 271, respectivement par rapport à la numérotation selon SEQ ID NO : 1. L'invention concerne également leur fabrication et leur utilisation. De telles protéases offrent de très bonnes performances de nettoyage.
(DE) Die Erfindung betrifft Proteasen umfassend eine Aminosäuresequenz, die mindestens 70 % Sequenzidentität mit der in SEQ ID NO:1 angegebenen Aminosäuresequenz über deren Gesamtlänge aufweist und (a) die Aminosäuresubstitution N130D an der Position, die der Position 30, bezogen auf die Nummerierung gemäß SEQ ID NO:1, entspricht, und (b) die eine Aminosäuresubstitution an mindestens einer der Positionen, die den Positionen 101, 133, 144, 224, 252 oder 271, jeweils bezogen auf die Nummerierung gemäß SEQ ID NO:1, entsprechen, aufweisen sowie deren Herstellung und Verwendung. Derartige Proteasen zeigen eine sehr gute Reinigungsleistung.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)