Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019048333) METHODS AND COMPOSITIONS FOR COUPLING NUCLEIC ACID TO A FUNCTIONALIZED SUPPORT
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/048333 International Application No.: PCT/EP2018/073353
Publication Date: 14.03.2019 International Filing Date: 30.08.2018
IPC:
C07H 21/00 (2006.01) ,C12N 15/10 (2006.01) ,C12Q 1/6834 (2018.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
10
Processes for the isolation, preparation or purification of DNA or RNA
[IPC code unknown for C12Q 1/6834]
Applicants:
LIFE TECHNOLOGIES AS [NO/NO]; Postboks 114 Smestad 0309 Oslo Norway, NO
Inventors:
JOBERT, Laure; NO
Agent:
LUDWIG, Christine; DE
Priority Data:
1714563.211.09.2017GB
Title (EN) METHODS AND COMPOSITIONS FOR COUPLING NUCLEIC ACID TO A FUNCTIONALIZED SUPPORT
(FR) PROCÉDÉS ET COMPOSITIONS POUR COUPLER UN ACIDE NUCLÉIQUE À UN SUPPORT FONCTIONNALISÉ
Abstract:
(EN) This invention relates to methods and compositions for coupling nucleic acid to a functionalized surface or support. In particular, the present invention provides an improved process for coupling aminated nucleic acid to a support functionalized with carboxylic acid groups, wherein the coupling reaction is conducted in the presence of an organic solvent. The invention further relates to compositions and kits for performing the coupling reaction and uses of nucleic acid-loaded supports for various applications.
(FR) La présente invention concerne des procédés et des compositions pour coupler un acide nucléique à une surface fonctionnalisée à ou un support fonctionnalisé. En particulier, la présente invention concerne un procédé amélioré pour coupler un acide nucléique aminé à un support fonctionnalisé avec des groupes acide carboxylique, la réaction de couplage étant conduite en présence d'un solvant organique. L'invention concerne en outre des compositions et des kits pour la mise en œuvre de la réaction de couplage et des utilisations de supports chargés d'acides nucléiques pour diverses applications.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)