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1. (WO2019047866) NOVEL THERAPEUTICS FOR CENTRAL NERVOUS SYSTEM DISORDERS
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Pub. No.: WO/2019/047866 International Application No.: PCT/CN2018/104225
Publication Date: 14.03.2019 International Filing Date: 05.09.2018
IPC:
C07C 279/26 (2006.01) ,C07C 279/00 (2006.01) ,A61K 31/155 (2006.01) ,A61K 31/215 (2006.01) ,A61P 25/00 (2006.01) ,A61P 37/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
279
Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups
20
containing any of the groups X being a hetero atom, Y being any atom, e.g. acylguanidines
24
Y being a hetero atom
26
X and Y being nitrogen atoms, i.e. biguanides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
279
Derivatives of guanidine, i.e. compounds containing the group the singly-bound nitrogen atoms not being part of nitro or nitroso groups
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
155
Amidines (), e.g. guanidine (H2N-C(NH)-NH2), isourea (HNC(OH)NH2), isothiourea (HNC(SH)-NH2)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
21
Esters, e.g. nitroglycerine, selenocyanates
215
of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
Applicants:
1GLOBE BIOMEDICAL CO., LTD. [CN/CN]; 8F, Block B, Techart Plaza No. 30 Xueyuan Road, Haidian District Beijing 100083, CN
1GLOBE HEALTH INSTITUTE LLC [US/US]; 333 Providence Hwy Norwood, MA 02062, US
Inventors:
LI, Chiang J.; US
CHEN, Suzhen; US
LIU, Jifeng; US
Agent:
CHOFN INTELLECTUAL PROPERTY; Room 1215-1218, Floor 12 Left Bank Community No. 68 Beisihuanxilu, Haidian District Beijing 100080, CN
Priority Data:
62/554,32605.09.2017US
Title (EN) NOVEL THERAPEUTICS FOR CENTRAL NERVOUS SYSTEM DISORDERS
(FR) NOUVEAUX AGENTS THÉRAPEUTIQUES DESTINÉS POUR DES TROUBLES DU SYSTÈME NERVEUX CENTRAL
Abstract:
(EN) Disclosed are novel compounds, pharmaceutical compositions and methods of preparation and use thereof for treating disease affecting the central nervous system such as multiple sclerosis.
(FR) L'invention concerne de nouveaux composés, des compositions pharmaceutiques et des procédés de préparation et d'utilisation de ceux-ci pour traiter une maladie affectant le système nerveux central tel que la sclérose en plaques.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)