Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019047824) NOVEL IMIDAZOQUINOLINE COMPOUND AND PREPARATION METHOD AND USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/047824 International Application No.: PCT/CN2018/103963
Publication Date: 14.03.2019 International Filing Date: 04.09.2018
IPC:
C07D 471/04 (2006.01) ,A61P 31/12 (2006.01) ,A61P 37/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12
Antivirals
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
Applicants:
浙江海正药业股份有限公司 ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. [CN/CN]; 中国浙江省台州市 椒江区外沙路46号 No.46 Waisha Road, Jiaojiang District Taizhou, Zhejiang 318000, CN
Inventors:
赵旭阳 ZHAO, Xuyang; CN
白骅 BAI, Hua; CN
徐肖杰 XU, Xiaojie; CN
刘礼飞 LIU, Lifei; CN
冯仁田 FENG, Rentian; CN
王海彬 WANG, Haibin; CN
林赟 LIN, Yun; CN
汪建洁 WANG, Jianjie; CN
董文献 DONG, Wenxian; CN
张文彪 ZHANG, Wenbiao; CN
程英雀 CHENG, Yingque; CN
李译 LI, Yi; CN
王二文 WANG, Erwen; CN
Agent:
北京邦信阳专利商标代理有限公司 BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE; 中国北京市 朝阳区光华路7号汉威大厦东区25A3-1室 Room 25A3-1, East Wing, Hanwei Plaza No.7 Guanghua Road, Chaoyang District Beijing 100020, CN
Priority Data:
201710792102.505.09.2017CN
Title (EN) NOVEL IMIDAZOQUINOLINE COMPOUND AND PREPARATION METHOD AND USE THEREOF
(FR) NOUVEAU COMPOSÉ D'IMIDAZOQUINOLINE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
(ZH) 新型咪唑喹啉化合物及其制备方法和用途
Abstract:
(EN) A novel imidazoquinoline compound and a preparation method of the compound. The compound represented by formula (I) or a pharmaceutically acceptable salt thereof has TLR7 and TLR8 agonist activities and can be used to treat cancer and to prevent or treat a viral infection.
(FR) L'invention concerne un nouveau composé d'imidazoquinoline et un procédé de préparation de celui-ci. L'invention concerne également un composé représenté par la formule (I) ou un sel pharmaceutiquement acceptable de celui-ci qui présente des activités agonistes de TLR7 et TLR8 et peut être utilisé dans le traitement du cancer ainsi que dans la prévention ou le traitement d'une infection virale.
(ZH) 一类新的咪唑喹啉化合物以及这类化合物的制备方法。这类由式(I)所表示的化合物或其药学上可接受的盐具有TLR7和TLR8激动活性,可以用于治疗癌症以及预防和治疗病毒感染。
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)