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1. (WO2019047812) PHARMACEUTICAL COMPOSITION OF DOCETAXEL CONJUGATE AND PREPARATION METHOD
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Pub. No.: WO/2019/047812 International Application No.: PCT/CN2018/103887
Publication Date: 14.03.2019 International Filing Date: 04.09.2018
IPC:
A61K 9/19 (2006.01) ,A61K 9/08 (2006.01) ,A61K 31/337 (2006.01) ,A61K 38/05 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
19
lyophilised
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
335
having oxygen as the only ring hetero atom, e.g. fungichromin
337
having four-membered rings, e.g. taxol
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
05
Dipeptides
Applicants:
深圳信立泰药业股份有限公司 SHENZHEN SALUBRIS PHARMACEUTICALS CO. LTD [CN/CN]; 中国广东省深圳市 福田区深南大道6009号车公庙绿景广场主楼37层 37F Main Tower, Lvjing plaza, Che Gong Miao No. 6009 Shennan Road, Futian District Shenzhen, Guangdong 518040, CN
Inventors:
刘刚 LIU, Gang; CN
张宣 ZHANG, Xuan; CN
成文明 CHENG, Wenming; CN
李硕 LI, Shuo; CN
温晓明 WEN, Xiaoming; CN
张倩立 ZHANG, Qianli; CN
Priority Data:
201710798308.907.09.2017CN
Title (EN) PHARMACEUTICAL COMPOSITION OF DOCETAXEL CONJUGATE AND PREPARATION METHOD
(FR) COMPOSITION PHARMACEUTIQUE DE CONJUGUÉ DE DOCÉTAXEL ET PROCÉDÉ DE PRÉPARATION
(ZH) 多西他赛共缀物的药物组合物及制备方法
Abstract:
(EN) The present invention belongs to the field of pharmaceutical manufacturing technology. The present invention provides a pharmaceutical composition of a docetaxel conjugate and a preparation method thereof. The pharmaceutical composition is preferably administered by injection. The docetaxel conjugate has a structural formula as shown in the following formula: (I).
(FR) La présente invention se rapporte au domaine de la technologie de fabrication pharmaceutique. La présente invention concerne une composition pharmaceutique d'un conjugué de docétaxel et un procédé de préparation correspondant. La composition pharmaceutique est, de préférence, administrée par injection. Le conjugué de docétaxel a une formule structurale telle que représentée dans la formule suivante : (I).
(ZH) 本发明属于医药制备技术领域,提供了一种多西他赛共缀物的药物组合物及其制备方法,所述药物组合物优选为通过注射给药,所述多西他赛共缀物具有如下式所述的结构式:(I)。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)