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1. (WO2019047439) USE OF BACTEROIDES FRAGILIS EXTRACT IN PREPARATION OF DRUG OR FOOD FOR PREVENTING AND TREATING IRRITABLE BOWEL SYNDROME
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Pub. No.: WO/2019/047439 International Application No.: PCT/CN2017/120112
Publication Date: 14.03.2019 International Filing Date: 29.12.2017
IPC:
C12N 1/20 (2006.01) ,A61K 35/74 (2015.01) ,A61K 31/715 (2006.01) ,A61P 1/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1
Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
20
Bacteria; Culture media therefor
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35
Medicinal preparations containing material or reaction products thereof with undetermined constitution
66
Materials from micro-organisms
74
Bacteria
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
715
Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
Applicants:
广州知易生物科技有限公司 GUANGZHOU ZHIYI PHARMACEUTICS INC. [CN/CN]; 中国广东省广州市 高新技术产业开发区瑞泰路2号A栋3楼 3th, Building A, No. 2 Ruitai Road High and New Development Zone Guangzhou, Guangdong 510530, CN
Inventors:
刘洋洋 LIU, Yangyang; CN
智发朝 ZHI, Fachao; CN
王晔 WANG, Ye; CN
白杨 BAI, Yang; CN
王从峰 WANG, Congfeng; CN
Agent:
广州华进联合专利商标代理有限公司 ADVANCE CHINA IP LAW OFFICE; 中国广东省广州市天河区珠江东路6号4501房 (部位:自编01-03和08-12单元)(仅限办公用途) Room 4501, No. 6 Zhujiang East Road, Tianhe District, Guangzhou Guangdong 510623, CN
Priority Data:
201710812676.411.09.2017CN
Title (EN) USE OF BACTEROIDES FRAGILIS EXTRACT IN PREPARATION OF DRUG OR FOOD FOR PREVENTING AND TREATING IRRITABLE BOWEL SYNDROME
(FR) UTILISATION D'UN EXTRAIT DE BACTEROIDES FRAGILIS DANS LA PRÉPARATION D'UN MÉDICAMENT OU D'UN ALIMENT EN VUE DE PRÉVENIR ET DE TRAITER LE SYNDROME DU CÔLON IRRITABLE
(ZH) 脆弱拟杆菌提取物在制备防治肠易激综合征的药物或食品中的应用
Abstract:
(EN) Disclosed is the use of a Bacteroides fragilis extract in the preparation of a drug or food for preventing and treating irritable bowel syndrome. The Bacteroides fragilis extract contains a capsular polysaccharide A in Bacteroides fragilis. The capsular polysaccharide A having a molecular weight of 5-70 KD extracted from CGMCC No.10685 Bacteroides fragilis ZY-312 has a better function in preventing and treating irritable bowel syndrome, and the effect thereof is better than that of a capsular polysaccharide A having a molecular weight of 110 kD extracted from Bacteroides fragilis NCTC 9343.
(FR) L'invention concerne l'utilisation d'un extrait de Bacteroides fragilis dans la préparation d'un médicament ou d'un aliment en vue de prévenir et de traiter le syndrome du côlon irritable. L'extrait de Bacteroides fragilis contient un polysaccharide capsulaire A dans Bacteroides fragilis. Le polysaccharide capsulaire A présentant un poids moléculaire de 5 à 70 KD extrait de CGMCC No.10685 Bacteroides fragilis ZY-312 présente une meilleure fonction dans la prévention et le traitement du syndrome du côlon irritable, et son effet est meilleur que celui d'un polysaccharide capsulaire A présentant un poids moléculaire de 110 kD extrait de Bacteroides fragilis NCTC 9343.
(ZH) 脆弱拟杆菌提取物在制备防治肠易激综合征的药物或食品中的应用,该脆弱拟杆菌提取物中含有脆弱拟杆菌荚膜多糖A。从CGMCCNo.10685脆弱拟杆菌ZY-312提取得到的分子量为5~70KD的荚膜多糖A具有更好的防治肠易激综合征的功能,其效果优于从脆弱拟杆菌NCTC 9343中提取得到的分子量为110KD的荚膜多糖A。
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African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
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Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)