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1. (WO2019046959) USE OF MIRTAZAPINE IN THE TREATMENT OF INFLAMMATORY DISORDERS, AUTOIMMUNE DISEASE AND PBC
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Pub. No.: WO/2019/046959 International Application No.: PCT/CA2018/051098
Publication Date: 14.03.2019 International Filing Date: 07.09.2018
IPC:
A61K 31/55 (2006.01) ,A61P 1/16 (2006.01) ,A61P 37/06 (2006.01) ,C07D 471/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
55
having seven-membered rings, e.g. azelastine, pentylenetetrazole
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
16
for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
02
Immunomodulators
06
Immunosuppressants, e.g. drugs for graft rejection
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
12
in which the condensed system contains three hetero rings
14
Ortho-condensed systems
Applicants:
UTI LIMITED PARTNERSHIP [CA/CA]; 3553 - 31st Street NW, Suite 100 Calgary, Alberta T2L 2K7, CA
Inventors:
SWAIN, Mark G.; CA
SHAHEEN, Abdel Aziz; CA
ALMISHRI, Wagdi; CA
KAPLAN, Gilaad G.; CA
Agent:
VICKERS, Mark F.; CA
BOOCOCK, Graeme R.; CA
DAMIANI, Michael; CA
EVENSON, Brandon; CA
FRITZ, Joachim T.; CA
WOOD, David; CA
ALLARD, Louis B.; CA
BEHMANN, Curtis B.; CA
DE KLEINE, Geoffrey; CA
HUNG, Shin; CA
KEELER, Todd; CA
MARSMAN, Kathleen E.; CA
NAUMAN, David A.; CA
PUNDSACK, Scott; CA
COGHLAN, Jeffrey; CA
GORDON, Jeff; CA
RAOUL, Jennifer; CA
SILVER, Gail C.; CA
SOJONKY, Andrew D.; CA
WEBB, Timothy; CA
ZIMMERMAN, Gord; CA
MUELLER-NEUHAUS, Jason R.; CA
Priority Data:
62/555,39707.09.2017US
Title (EN) USE OF MIRTAZAPINE IN THE TREATMENT OF INFLAMMATORY DISORDERS, AUTOIMMUNE DISEASE AND PBC
(FR) UTILISATION DE MIRTAZAPINE DANS LE TRAITEMENT DE TROUBLES INFLAMMATOIRES, DE MALADIES AUTO-IMMUNES ET DE LA CBP
Abstract:
(EN) There is described herein the use of mirtazapine in methods for the treatment of inflammatory disorders, autoimmune disease, and PBC.
(FR) L'invention concerne l'utilisation de mirtazapine dans des procédés pour le traitement de troubles inflammatoires, d'une maladie auto-immune et de la CBP (cirrhose biliaire primitive).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)