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1. (WO2019046690) AN INJECTION MOLDED MICROFLUIDIC/FLUIDIC CARTRIDGE INTEGRATED WITH SILICON-BASED SENSOR
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Pub. No.: WO/2019/046690 International Application No.: PCT/US2018/049039
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
B01L 3/00 (2006.01) ,B81C 1/00 (2006.01) ,B81B 1/00 (2006.01) ,B81B 3/00 (2006.01) ,B81B 7/00 (2006.01) ,B81C 3/00 (2006.01) ,B81C 99/00 (2010.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
C
PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICRO-STRUCTURAL DEVICES OR SYSTEMS
1
Manufacture or treatment of devices or systems in or on a substrate
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
B
MICRO-STRUCTURAL DEVICES OR SYSTEMS, e.g. MICRO-MECHANICAL DEVICES
1
Devices without movable or flexible elements, e.g. micro-capillary devices
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
B
MICRO-STRUCTURAL DEVICES OR SYSTEMS, e.g. MICRO-MECHANICAL DEVICES
3
Devices comprising flexible or deformable elements, e.g. comprising elastic tongues or membranes
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
B
MICRO-STRUCTURAL DEVICES OR SYSTEMS, e.g. MICRO-MECHANICAL DEVICES
7
Micro-structural systems
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
C
PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICRO-STRUCTURAL DEVICES OR SYSTEMS
3
Assembling of devices or systems from individually processed components
B PERFORMING OPERATIONS; TRANSPORTING
81
MICRO-STRUCTURAL TECHNOLOGY
C
PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICRO-STRUCTURAL DEVICES OR SYSTEMS
99
Subject matter not provided for in other groups of this subclass
Applicants:
COMPLETE GENOMICS, INC. [US/US]; 2904 Orchard Parkway San Jose, California 95134, US
Inventors:
LI, Chen; US
ZHONG, Cheng Frank; US
LIU, Yu; US
OUYANG, Yiwen; US
Agent:
KITCES, Matthew T.; US
APPLE, Randolph T.; US
Priority Data:
62/553,61401.09.2017US
Title (EN) AN INJECTION MOLDED MICROFLUIDIC/FLUIDIC CARTRIDGE INTEGRATED WITH SILICON-BASED SENSOR
(FR) UNE CARTOUCHE MICROFLUIDIQUE/FLUIDIQUE MOULÉE PAR INJECTION INTÉGRÉE AVEC CAPTEUR À BASE DE SILICIUM
Abstract:
(EN) A microfluidic device includes a substrate, a sensor, and one or more lamination films. The top surface of the substrate can include first recessed grooves forming first open channels and the bottom surface of the plastic substrate can include a first recessed cavity and second recessed groves forming second open channels. A first lamination film can be adhered with the top surface of the plastic substrate to form first closed channels. A second lamination film can be adhered to the bottom surface of the plastic substrate to form second closed channels. The sensor can be on the bottom surface of the substrate such that it overlies the first recessed cavity to form a flow cell with the sensor top surface inward facing. A first closed channel can be fluidically connected with a second closed channel and a first or second closed channel can be fluidically connected with the flow cell.
(FR) Un dispositif microfluidique comprend un substrat, un capteur et un ou plusieurs pellicules de laminage. La surface supérieure du substrat peut comprendre des premiers sillons formant des premiers canaux ouverts et la surface inférieure du substrat en plastique peut comprendre un premier sillon et des seconds sillons formant des seconds canaux ouverts. Une première pellicule de laminage peut être collée à la surface supérieure du substrat en plastique pour former des premiers canaux fermés. Une seconde pellicule de laminage peut être collée à la surface inférieure du substrat en plastique pour former des seconds canaux fermés. Le capteur peut être situé sur la surface inférieure du substrat de manière à recouvrir le premier sillon afin de former une cuve à circulation avec la surface supérieure du capteur tournée vers l'intérieur. Un premier canal fermé peut être en communication fluidique avec un second canal fermé et un premier ou un second canal fermé peut être en communication fluidique avec la cuve à circulation.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)