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1. (WO2019046564) TRANSPOSASE COMPOSITIONS, METHODS OF MAKING AND METHODS OF SCREENING
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Pub. No.: WO/2019/046564 International Application No.: PCT/US2018/048823
Publication Date: 07.03.2019 International Filing Date: 30.08.2018
IPC:
C12Q 1/6811 (2018.01) ,C12N 15/10 (2006.01)
[IPC code unknown for C12Q 1/6811]
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
10
Processes for the isolation, preparation or purification of DNA or RNA
Applicants:
SCHABORT, Du Toit [ZA/ZA]; ZA
KAPA BIOSYSTEMS, INC. [US/US]; 200 Ballardvale Street, Suite 250 Wilmington, Massachusetts 01887, US
Inventors:
SCHABORT, Du Toit; ZA
FAURHOLM, Bjarne; ZA
BOURN, William; ZA
RANIK, Martin; ZA
HUDDY, Suzanne; US
ALLIE, Raeeza; US
BERRY, Michael Stuart; US
Agent:
MILLER, Katherine J.; US
ELRIFI, Ivor R.; US
Priority Data:
62/552,21430.08.2017US
Title (EN) TRANSPOSASE COMPOSITIONS, METHODS OF MAKING AND METHODS OF SCREENING
(FR) COMPOSITIONS DE TRANSPOSASE, LEURS PROCÉDÉS DE PRÉPARATION ET PROCÉDÉS DE CRIBLAGE
Abstract:
(EN) The disclosure provides compositions and methods for high-throughput screening a plurality of transposases to identify rare mutations that affect desired features of the transposase. Compositions of the disclosures are provided that facilitate the high-throughput screening methods of the disclosure.
(FR) L'invention concerne des compositions et des procédés de criblage à haut débit d'une pluralité de transposases pour identifier des mutations rares qui affectent les caractéristiques souhaitées de la transposase. L'invention concerne des compositions qui facilitent les procédés de criblage à haut débit selon l'invention.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)