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1. (WO2019046557) DEVICES AND METHODS FOR PROCESSING FLUID SAMPLES
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Pub. No.: WO/2019/046557 International Application No.: PCT/US2018/048809
Publication Date: 07.03.2019 International Filing Date: 30.08.2018
IPC:
G01N 33/543 (2006.01) ,G01N 27/447 (2006.01) ,C12M 1/34 (2006.01) ,C12M 1/42 (2006.01) ,B01L 3/00 (2006.01) ,B01J 19/08 (2006.01) ,B01D 57/02 (2006.01) ,B01J 19/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
416
Systems
447
using electrophoresis
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
34
Measuring or testing with condition measuring or sensing means, e.g. colony counters
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
42
Apparatus for the treatment of micro-organisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19
Chemical, physical, or physico-chemical processes in general; Their relevant apparatus
08
Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
57
Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C123
02
by electrophoresis
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19
Chemical, physical, or physico-chemical processes in general; Their relevant apparatus
Applicants:
UNIVERSITY OF CINCINNATI [US/US]; 2900 Reading Road Suite 460N Cincinnati, OH 45206-0829, US
Inventors:
HEIKENFELD, Jason, Charles; US
JAJACK, Andrew; US
GOMEZ, Eliot; US
BROTHERS, Michael, Charles; US
STAMPER, Isaac; US
Agent:
ARDIZZONE, Timothy, D.; US
BELLAMY, Glenn, D.; US
AHRENS, Gregory, F.; US
BENINTENDI, Steven, W.; US
BIEBER, John, H.; US
Priority Data:
62/551,82630.08.2017US
Title (EN) DEVICES AND METHODS FOR PROCESSING FLUID SAMPLES
(FR) DISPOSITIFS ET PROCÉDÉS DE TRAITEMENT D'ÉCHANTILLONS DE FLUIDE
Abstract:
(EN) Described are devices for and methods of modulating a fluid sample. The devices (10, 40, 60, 80, 100, 130, 160, 220) include at least one sample-modulating component (20, 76, 78, 90, 110, 112, 116, 150, 152, 154, 162, 164, 182, 184, 186, 222, and 230) and, in some embodiments, two or more sample-modulating components. The sample-modulating components are each capable of performing a function selected from the following group: concentrating the sample to increase a concentration of a first constituent of the sample; diluting the sample to decrease a concentration of a second constituent in of the sample; desalinating the sample to decrease the total moles of salt in the sample volume or causing a temporary decrease in the osmolarity; adjusting pH of the sample to bring a pH of the sample into a predetermined range; absorbing one or more nonpolar substances to decrease a concentration of the nonpolar substances; and delivering one or more reagents to the sample to provide a desired concentration of the reagent in the sample.
(FR) L'invention concerne des dispositifs et des procédés de modulation d'un échantillon de fluide. Les dispositifs 10, 40, 60, 80, 100, 130, 160, 220 comprennent au moins un composant de modulation d'échantillon 20, 76, 78, 90, 110, 112, 116, 150, 152, 154, 162, 164, 182, 184, 186, 222, et 230 et, dans certains modes de réalisation, au moins deux composants de modulation d'échantillon. Chaque composant de modulation d'échantillon est capable de remplir une fonction choisie dans le groupe suivant : concentrer l'échantillon pour augmenter la concentration d'un premier constituant de l'échantillon; diluer l'échantillon pour réduire la concentration d'un second constituant de l'échantillon; dessaler l'échantillon pour réduire les moles totales de sel dans le volume d'échantillon ou provoquer une baisse temporaire de l'osmolarité; ajuster le pH de l'échantillon pour amener le pH de l'échantillon dans une plage prédéfinie; absorber une ou plusieurs substances non polaires pour réduire une concentration desdites substances non polaires; et distribuer un ou plusieurs réactifs dans l'échantillon pour obtenir une concentration souhaitée du réactif dans l'échantillon.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)