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1. (WO2019046556) COMPOUNDS, COMPOSITIONS, KITS, AND METHODS FOR ACTIVATING IMMUNE CELLS AND/OR AN IMMUNE SYSTEM RESPONSE
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/046556 International Application No.: PCT/US2018/048806
Publication Date: 07.03.2019 International Filing Date: 30.08.2018
IPC:
A61K 31/5575 (2006.01) ,A61K 9/00 (2006.01) ,A61K 45/06 (2006.01) ,C07C 235/78 (2006.01) ,C07C 405/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
557
Eicosanoids, e.g. leukotrienes
5575
having a cyclopentane ring, e.g. prostaglandin E2, prostaglandin F2-alpha
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
235
Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
70
having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
72
with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
76
of an unsaturated carbon skeleton
78
the carbon skeleton containing rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
405
Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins
Applicants:
EAST CAROLINA UNIVERSITY [US/US]; 210 Spilman Building Greenville, North Carolina 27858, US
Inventors:
VAN DROSS-ANDERSON, Rukiyah T.; US
ESCOBEDO, Rene; US
Agent:
BOBAY, Erin, R.; US
Priority Data:
62/553,51001.09.2017US
Title (EN) COMPOUNDS, COMPOSITIONS, KITS, AND METHODS FOR ACTIVATING IMMUNE CELLS AND/OR AN IMMUNE SYSTEM RESPONSE
(FR) COMPOSÉS, COMPOSITIONS, KITS ET PROCÉDÉS POUR ACTIVER DES CELLULES IMMUNITAIRES ET/OU UNE RÉPONSE DE SYSTÈME IMMUNITAIRE
Abstract:
(EN) Provided is a method of activating immune cells and/or an immune system response in a subject. The method may comprise administering to a subject an effective amount of a compound of Formula (I): or a prodrug, derivative, and/or salt thereof. In some embodiments, the method comprises contacting an immune cell with a compound of Formula (I) or a prodrug, derivative, and/or salt thereof. Also provided are compounds, compositions, and kits for activating immune cells and/or an immune system response in a subject.
(FR) La présente invention concerne un procédé d'activation de cellules immunitaires et/ou une réponse de système immunitaire chez un sujet. Le procédé peut comprendre l’administration au sujet d’une quantité active d’un composé répondant à la Formule (I) : ou de l’un des promédicaments, dérivés et/ou sels de celui-ci. Dans certains modes de réalisation, le procédé comprend la mise en contact d'une cellule immunitaire avec un composé de Formule (I) ou l’un des promédicaments, dérivés et/ou sels de celui-ci. L'invention concerne également des composés, des compositions et des kits pour activer des cellules immunitaires et/ou une réponse de système immunitaire chez un sujet.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)