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1. (WO2019045783) SYSTEM AND METHODS FOR BILIRUBIN ANALYSIS
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Pub. No.: WO/2019/045783 International Application No.: PCT/US2018/027809
Publication Date: 07.03.2019 International Filing Date: 16.04.2018
IPC:
G01N 27/02 (2006.01) ,G01N 27/327 (2006.01) ,G01N 33/72 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
02
by investigating impedance
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27
Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26
by investigating electrochemical variables; by using electrolysis or electrophoresis
28
Electrolytic cell components
30
Electrodes, e.g. test electrodes; Half-cells
327
Biochemical electrodes
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
72
involving blood pigments, e.g. hemoglobin, bilirubin
Applicants:
NEOLIGHT LLC [US/US]; 1475 N. Scottsdale Road, Suite 200 Scottsdale, AZ 85257, US
Inventors:
PALANISWAMY, Sivakumar; US
KRISHNARAJU, Deepakshyam; US
PEACOCK, Martin; GB
Agent:
JORDAN, Jonathan, A.; US
Priority Data:
62/552,22630.08.2017US
Title (EN) SYSTEM AND METHODS FOR BILIRUBIN ANALYSIS
(FR) SYSTÈME ET PROCÉDÉS D'ANALYSE DE LA BILIRUBINE
Abstract:
(EN) A method for measuring bilirubin levels in a subject. The method can include the steps of providing a sample to be measured from the subject, wherein the sample comprises bilirubin bound to albumin; adding a release agent to the sample, the release agent configured to release the bound bilirubin from the albumin; measuring electrochemical data of the sample using an electrochemical cell; and determining a total serum bilirubin concentration of the sample using the electrochemical data. This method is capable of providing a simpler, faster, and more robust measurement when compared to traditional bilirubin assay methods.
(FR) L'invention concerne un procédé de mesure de taux de bilirubine chez un sujet. Le procédé peut comprendre les étapes consistant à fournir un échantillon à mesurer issu du sujet, l'échantillon comprenant de la bilirubine liée à de l'albumine; ajouter un agent de libération à l'échantillon, l'agent de libération étant conçu pour libérer de l'albumine la bilirubine liée; mesurer des données électrochimiques de l'échantillon à l'aide d'une cellule électrochimique; et déterminer une concentration sérique totale en bilirubine de l'échantillon à l'aide des données électrochimiques. Le procédé permet de fournir une mesure plus simple, plus rapide et plus robuste en comparaison avec les procédés classiques de dosage de la bilirubine.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)