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1. (WO2019045529) SELF-ASSEMBLING PARTICLES AND METHOD FOR PREPARING SAME
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Pub. No.: WO/2019/045529 International Application No.: PCT/KR2018/010171
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
A61K 39/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
주식회사 휴벳바이오 HUVET BIO, INC. [KR/KR]; 서울시 서초구 반포대로28길 43, 502호 (서초동, 아이센스빌딩) (i-sens Bldg., Seocho-dong) 502, 43, Banpo-daero 28-gil, Seocho-gu, Seoul 06646, KR
Inventors:
함승주 HAAM, Seungjoo; KR
김현욱 KIM, Hyun-Ouk; KR
박근선 PARK, Geun Seon; KR
임종우 LIM, Jong Woo; KR
천해진 CHUN, Hae Jin; KR
송대섭 SONG, Daesub; KR
나운성 NA, Woon Sung; KR
염민주 YEOM, Min Joo; KR
Agent:
특허법인 다나 DANA PATENT LAW FIRM; 서울시 강남구 역삼로 3길 11 광성빌딩 신관 5층 5th Floor, New Wing, Gwangsung Bldg., 11, Yeoksam-ro 3-gil, Gangnam-gu, Seoul 06242, KR
Priority Data:
10-2017-011110431.08.2017KR
Title (EN) SELF-ASSEMBLING PARTICLES AND METHOD FOR PREPARING SAME
(FR) PARTICULES AUTO-ASSEMBLANTES ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(KO) 자가 조립형 입자 및 이의 제조방법
Abstract:
(EN) The present invention relates to immuno-directed particles in which an antigenic protein-amphipathic macromolecule polymer is self-assembled, wherein when using the immuno-directed particles of the present invention, it is possible to induce more immune responses even with a smaller amount of vaccine as compared with a conventional vaccine which simply contains an antigenic protein in a carrier, and to provide an efficient vaccine platform in which side effects such as infections of viral diseases can be eliminated.
(FR) La présente invention concerne des particules immuno-dirigées dans lesquelles un polymère macromoléculaire amphipathique à protéine antigénique est auto-assemblé, l'induction d'un plus grand nombre de réponses immunitaires même avec une quantité plus petite de vaccin étant possible lors de l'utilisation des particules immuno-dirigées de la présente invention comparé à un vaccin classique qui contient simplement une protéine antigénique dans un vecteur. L'invention concerne également une plateforme de vaccin efficace, les effets secondaires tels que des infections de maladies virales pouvant être éliminés.
(KO) 본 발명은 항원단백질-양친매성 고분자 중합체가 자가 조립된 면역유도 입자에 관한 것으로, 본 발명의 면역유도 입자를 이용하는 경우 항원 단백질을 단순히 담체에 포함하는 종래의 백신과 비교해서 더 적은 백신의 양으로도 더욱 많은 면역반응을 유도할 수 있고, 바이러스 질환이 감염과 같은 부작용은 배제할 수 있는 효율적인 백신 플랫폼을 제공할 수 있다.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)