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1. (WO2019045452) METHOD FOR TREATING TNFα-RELATED DISEASE
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Pub. No.: WO/2019/045452 International Application No.: PCT/KR2018/009998
Publication Date: 07.03.2019 International Filing Date: 29.08.2018
IPC:
C07K 16/24 (2006.01) ,A61K 9/00 (2006.01) ,A61K 47/14 (2006.01) ,A61K 47/26 (2006.01) ,A61K 47/18 (2006.01) ,A61K 39/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
24
against cytokines, lymphokines or interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
08
containing oxygen
14
Esters of carboxylic acids
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
16
containing nitrogen
18
Amines; Quaternary ammonium compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
(주)셀트리온 CELLTRION INC. [KR/KR]; 인천시 연수구 아카데미로 23 23, Academy-ro Yeonsu-gu Incheon 22014, KR
Inventors:
김선정 KIM, Sun Jung; KR
서지혜 SUH, Jee Hye; KR
안현철 AN, Hyun Chul; KR
이성영 LEE, Sung Young; KR
Priority Data:
10-2017-011042630.08.2017KR
10-2017-014452101.11.2017KR
10-2018-001744913.02.2018KR
Title (EN) METHOD FOR TREATING TNFα-RELATED DISEASE
(FR) MÉTHODE DE TRAITEMENT D'UNE MALADIE LIÉE AU TNFα
(KO) TNFα 관련 질환을 치료하는 방법
Abstract:
(EN) The present invention relates to a method for treating a TNFα-related disease by subcutaneously administering an antibody (anti-TNFα antibody) or an antigen-binding fragment thereof that binds to TNFα. The treatment method, composition, kit or use thereof according to the present invention provides an advantage of increased patient satisfaction, through the improvement of convenience and enhancement of the quality of life, by reducing the time taken for administration compared to intravenous injections and decreasing the time that patients stay in a hospital.
(FR) La présente invention concerne une méthode de traitement d'une maladie liée au TNFα par administration sous-cutanée d'un anticorps (anticorps anti-TNFα) ou d'un fragment de liaison à l'antigène de celui-ci qui se lie au TNFα. La méthode de traitement, la composition, le kit ou l'utilisation de ceux-ci, selon la présente invention offrent l'avantage d'augmenter la satisfaction du patient, par l'amélioration de la commodité et de la qualité de vie, en réduisant le temps nécessaire à l'administration par rapport aux injections intraveineuses et en diminuant le temps de séjour des patients dans un hôpital.
(KO) 본 발명은 TNFα에 결합하는 항체 (항-TNFα 항체) 또는 이의 항원 결합 단편을 피하로 투여하여 TNFα 관련 질환을 치료하는 방법에 관한 것이다. 본 발명에 따른 치료 방법, 조성물, 키트 또는 용도는 정맥 주사에 비해 투여 받는 시간이 줄고, 환자들이 병원에 머무르는 시간이 감소함으로써, 편의성 개선과 삶의 질 향상을 통해 환자 만족도가 상승하는 이점을 제공한다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)