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1. (WO2019043693) SYSTEM AND METHOD FOR SEPARATION OF CHIRAL COMPOUNDS USING MAGNETIC INTERACTIONS
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Pub. No.: WO/2019/043693 International Application No.: PCT/IL2018/050942
Publication Date: 07.03.2019 International Filing Date: 26.08.2018
IPC:
G01N 30/00 (2006.01) ,B01D 7/02 (2006.01) ,B01D 9/00 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
7
Sublimation
02
Crystallisation directly from the vapour phase
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
9
Crystallisation
Applicants:
YEDA RESEARCH AND DEVELOPMENT CO. LTD. [IL/IL]; At The Weizmann Institute Of Science P.O.Box 95 7610002 Rehovot, IL
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. [IL/IL]; Hi -Tech Park, Givat-Ram P.O. Box 39135 9139002 Jerusalem, IL
Inventors:
NAAMAN, Ron; IL
CAPUA, Eyal; IL
LAHAV, Meir; IL
TASSINARI, Francesco; IL
PALTIEL, Yossef; IL
YOCHELIS, Shira; IL
Agent:
TAUBER, Gilad; IL
Priority Data:
25420929.08.2017IL
62/620,50323.01.2018US
62/636,90301.03.2018US
Title (EN) SYSTEM AND METHOD FOR SEPARATION OF CHIRAL COMPOUNDS USING MAGNETIC INTERACTIONS
(FR) SYSTÈME ET PROCÉDÉ DE SÉPARATION DE COMPOSÉS CHIRAUX PAR INTERACTIONS MAGNÉTIQUES
Abstract:
(EN) Systems and methods are disclosed for use in the separation of chiral compounds, and enantiomers in particular. The system comprises a cavity (110) for containing a fluid mixture that comprises one or more types of chiral molecules, which may also include enantiomers, and at least one ferromagnetic or paramagnetic substrate (120) providing at least one interface (130) with said fluid mixture. The substrate (120) is magnetized providing a magnetic field Bz perpendicular to said ferromagnetic or paramagnetic interface (130), thereby providing a variation in the interaction energy of chiral molecules of different handedness, aka. enantiomers, with said substrate (120).
(FR) La présente invention concerne un système et des procédés destinés à être utilisés dans la séparation de composés chiraux, et des énantiomères en particulier. Le système comprend : une cavité (110) configurée pour contenir un mélange de fluides qui comprend un ou plusieurs types de molécules chirales, qui peuvent également comprendre des énantiomères, et au moins un substrat ferromagnétique ou paramagnétique (120) fournissant au moins une interface (130) avec ledit mélange de fluides. Le substrat (120) est magnétisé en fournissant un champ magnétique Bz perpendiculaire à ladite interface ferromagnétique ou paramagnétique (130), ce qui permet de fournir une variation de l'énergie d'interaction entre des molécules chirales de chiralité différente, ou énantiomères, avec ledit substrat (120).
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)