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1. (WO2019043614) METHOD FOR PREPARING GRANULES
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Pub. No.: WO/2019/043614 International Application No.: PCT/IB2018/056629
Publication Date: 07.03.2019 International Filing Date: 30.08.2018
IPC:
A61K 9/16 (2006.01) ,A61K 9/20 (2006.01) ,A61K 31/192 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
20
Pills, lozenges or tablets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
192
having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
Applicants:
NOVARTIS AG [CH/CH]; Lichtstrasse 35 4056 Basel, CH
Inventors:
DE WAARD, Hans; CH
KRUMME, Markus; CH
SCHMIDT, Adrian; CH
TAILLEMITE, Julien; CH
MOLL, Klaus-Peter; CH
Agent:
NOVARTIS PHARMA AG; POSTFACH 4002 Basel, CH
Priority Data:
17188800.131.08.2017EP
Title (EN) METHOD FOR PREPARING GRANULES
(FR) PROCÉDÉ POUR LA PRÉPARATION DE GRANULÉS
Abstract:
(EN) In a method for preparing granules a slurry containing solid API powder particles dispersed in a liquid is prepared. The slurry is fed to a granulator (16) and mixed with a dry base powder within the granulator (16) in order to produce a slurry/base powder mixture. The slurry/base powder mixture produced within the granulator (16) is dried in order to obtain granules containing the solid API particles and the base powder.
(FR) Dans un procédé pour la préparation de granulés, une suspension épaisse, contenant des particules de poudre de principe actif pharmaceutique solide dispersées dans un liquide, est préparée. La suspension épaisse est introduite dans un granulateur (16) et mélangée avec une poudre sèche de base à l'intérieur du granulateur (16) afin de produire un mélange de suspension épaisse/poudre de base. Le mélange de suspension épaisse/poudre de base produit à l'intérieur du granulateur (16) est séché afin d'obtenir des granulés contenant les particules de principe actif pharmaceutique solide et la poudre de base.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)