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1. (WO2019043198) METHODS AND DEVICES FOR ACOUSTOPHORETIC OPERATIONS IN POLYMER CHIPS
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Pub. No.: WO/2019/043198 International Application No.: PCT/EP2018/073542
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
B01L 3/00 (2006.01) ,G01N 15/10 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
L
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3
Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15
Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10
Investigating individual particles
Applicants:
ACOUSORT AB [SE/SE]; Medicon Village 223 81 LUND, SE
Inventors:
BRUUS, Henrik; DK
MOISEYENKO, Rayisa; DK
FRELTOFT, Torsten; DK
OHLSSON, Pelle; SE
JAKOBSSON, Ola; SE
Agent:
BRANN AB; Box 3690 103 59 Stockholm, SE
Priority Data:
17188920.731.08.2017EP
Title (EN) METHODS AND DEVICES FOR ACOUSTOPHORETIC OPERATIONS IN POLYMER CHIPS
(FR) PROCÉDÉS ET DISPOSITIFS POUR DES OPÉRATIONS ACOUSTOPHORÉTIQUES DANS DES PUCES POLYMÈRES
Abstract:
(EN) The invention relates to a method of performing an acoustophoretic operation, comprising the steps of: a. providing an acoustophoretic chip comprising a polymer substrate in which a microfluidic flow channel is positioned, b. providing at least one ultrasound transducer in acoustic contact with one surface of the substrate, c. actuating the at least one ultrasound transducer at a frequency f that corresponds to an acoustic resonance peak of the substrate including the microfluidic flow channel filled with a liquid suspension,and d. providing the liquid suspension in the flow channel to perform the acoustophoretic operation on the liquid suspension.The invention further relates to an acoustophoretic device, a method of producing an acoustophoretic device, and a microfluidic system comprising the acoustophoretic device.
(FR) L'invention concerne un procédé de réalisation d'une opération acoustophorétique, comprenant les étapes : a. fourniture d'une puce acoustophorétique comprenant un substrat polymère dans lequel est positionné un canal d'écoulement microfluidique, b. fourniture d'au moins un transducteur ultrasonore en contact acoustique avec une surface du substrat, c. actionnement du ou des transducteurs ultrasonores à une fréquence f qui correspond à un pic de résonance acoustique du substrat comprenant le canal d'écoulement microfluidique rempli d'une suspension liquide, et d. fourniture de la suspension liquide dans le canal d'écoulement pour effectuer l'opération acoustophorétique sur la suspension liquide. L'invention concerne en outre un dispositif acoustophorétique, un procédé de production d'un dispositif acoustophorétique, et un système microfluidique comprenant le dispositif acoustophorétique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)