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1. (WO2019043192) TLR-9 AGONISTS FOR MODULATION OF TUMOR MICROENVIRONMENT
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Pub. No.: WO/2019/043192 International Application No.: PCT/EP2018/073534
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
A61P 35/00 (2006.01) ,A61K 31/7088 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7088
Compounds having three or more nucleosides or nucleotides
Applicants:
MOLOGEN AG [DE/DE]; Fabeckstrasse 30 14195 Berlin, DE
Inventors:
KAPP, Kerstin; DE
SCHMIDT, Manuel; DE
Agent:
VON RENESSE, Dorothea; DE
KÖNIG, Gregor; DE
KÖNIG, Reimar Dr.; DE
HERTZSCH, Claudia; DE
BENIK, Victoria; DE
HEMSATH, Lars; DE
LÜCKE, Robert; DE
TILMANN, Max W.; DE
ROTH, Carla; DE
VERHASSELT, Jörn; DE
SMORODIN, Tobias; DE
SZYNKA, Dirk; DE
Priority Data:
17001465.831.08.2017EP
18151734.315.01.2018EP
Title (EN) TLR-9 AGONISTS FOR MODULATION OF TUMOR MICROENVIRONMENT
(FR) AGONISTES DE TLR-9 POUR LA MODULATION DU MICROENVIRONNEMENT TUMORAL
Abstract:
(EN) A TLR-9 agonist for use in the treatment of a tumor disease, in particular of colon cancer, and for the modulation of the tumor microenvironment.
(FR) L'invention concerne un agoniste de TLR-9 destiné à être utilisé dans le traitement d'une maladie tumorale, en particulier du cancer du côlon, et pour la modulation du microenvironnement tumoral.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)