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1. (WO2019043187) LATERAL FLOW ASSAY FOR DETECTING THE PRESENCE OF A SPECIFIC MAMMALIAN CELL OR BACTERIA IN A BIOLOGICAL SAMPLE
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/043187 International Application No.: PCT/EP2018/073525
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
G01N 33/573 (2006.01) ,C07H 21/00 (2006.01) ,C12Q 1/68 (2018.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
573
for enzymes or isoenzymes
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21
Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
SOMAPROBES SL [ES/ES]; Paseo Mikeletegi 83, Floor 3, Lab 8. 20009 San Sebastián, ES
Inventors:
HERNÁNDEZ HINCAPIÉ, Frank J.; ES
HERNANDEZ, Luiza Iuliana; ES
JIMENEZ TRUJILLO, Tania; ES
Agent:
HOFFMANN EITLE S.L.U.; Paseo de la Castellana 140 Planta 3ª. Edificio Lima 28046 Madrid, ES
Priority Data:
17382590.231.08.2017EP
Title (EN) LATERAL FLOW ASSAY FOR DETECTING THE PRESENCE OF A SPECIFIC MAMMALIAN CELL OR BACTERIA IN A BIOLOGICAL SAMPLE
(FR) DOSAGE À ÉCOULEMENT LATÉRAL POUR DÉTECTER LA PRÉSENCE D’UNE CELLULE DE MAMMIFÈRE OU D’UNE BACTÉRIE SPÉCIFIQUE DANS UN ÉCHANTILLON BIOLOGIQUE
Abstract:
(EN) The present invention provides for a rapid and sensitive molecular approach for bacterial infections as well as for tumors for clinical diagnosis.For that purpose, the present invention provides for an in vitro use in a lateral flow assay of a polynucleotide sequence susceptible of being cleaved by a specific nuclease derived from a bacteria or a mammalian cell, wherein the polynucleotide sequence (also named "Substrate") is characterized by comprising a capture tag and a reporter molecule at each end of the sequence, for detecting the presence of a specific mammalian cell or bacteria in a biological sample.
(FR) La présente invention concerne une approche moléculaire rapide et sensible pour des infections bactériennes ainsi que pour des tumeurs pour un diagnostic clinique. À cet effet, la présente invention concerne une utilisation in vitro dans un dosage à écoulement latéral d’une séquence polynucléotidique susceptible d’être clivée par une nucléase spécifique dérivée d’une bactérie ou d’une cellule de mammifère, la séquence polynucléotidique (également appelée "substrat") étant caractérisée en ce qu’elle comprend une étiquette de capture et une molécule de rapporteur à chaque extrémité de la séquence, pour détecter la présence d’une cellule de mammifère ou d’une bactérie spécifique dans un échantillon biologique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)