Some content of this application is unavailable at the moment.
If this situation persist, please contact us atFeedback&Contact
1. (WO2019043029) PROCESS FOR PURIFYING SIALYLATED OLIGOSACCHARIDES
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/043029 International Application No.: PCT/EP2018/073178
Publication Date: 07.03.2019 International Filing Date: 29.08.2018
IPC:
C07H 1/08 (2006.01) ,C07H 3/06 (2006.01) ,A23L 1/308 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
1
Processes for the preparation of sugar derivatives
06
Separation; Purification
08
from natural products
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
3
Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
06
Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1
Foods or foodstuffs; Their preparation or treatment
29
Modifying nutritive qualities of foods; Dietetic products
307
Reducing nutritive value; Dietetic products with reduced nutritive value
308
Addition of substantially indigestible substances, e.g. dietary fibres
Applicants:
JENNEWEIN BIOTECHNOLOGIE GMBH [DE/DE]; Maarweg 32 53619 Rheinbreitbach, DE
Inventors:
JENNEWEIN, Stefan; DE
HELFRICH, Markus; DE
ENGELS, Benedikt; DE
Agent:
RCD PATENT GIESEN, SCHMELCHER & GRIEBEL PATENTANWÄLTE PARTNERSCHAFT GMBB; Kaiserstr. 100 52134 Herzogenrath, DE
Priority Data:
17188280.629.08.2017EP
Title (EN) PROCESS FOR PURIFYING SIALYLATED OLIGOSACCHARIDES
(FR) PROCÉDÉ DE PURIFICATION D'OLIGOSACCHARIDES SIALYLÉS
Abstract:
(EN) Disclosed is a method for purifying sialylated oligosaccharides from a fermentation broth, cell-lysate or biocatalytic reaction mixture for obtaining high amounts of desired sialylated oligosaccharides in high purity. The method is particular suitable for the large-scale economic purification of sialylated human milk oligosaccharides (such as 3ʹ-sialyllactose, 6ʹ-sialyllactose or sialylated lacto-N-tetraose derivatives) from microbial fermentation, using recombinant bacterial cells or yeast cells. The obtained material is of high purity and can be used for food or medical application such like medical nutrition products, infant formula, dietary supplements, general nutrition products (e.g. dairy drinks).
(FR) L'invention concerne un procédé de purification d'oligosaccharides sialylés à partir d'un bouillon de fermentation, d'un lysat cellulaire ou d'un mélange réactionnel biocatalytique pour obtenir des quantités élevées d'oligosaccharides sialylés recherchés de grande pureté. Le procédé est particulièrement approprié pour la purification économique à grande échelle d'oligosaccharides de lait humain sialylés (tels que 3'-sialyllactose, 6'-sialyllactose ou des dérivés de lacto-N-tétraose sialylés) à partir d'une fermentation microbienne, à l'aide de cellules bactériennes recombinantes ou de cellules de levure. Le matériau obtenu est de haute pureté et peut être utilisé pour des applications alimentaires ou médicales telles que des produits de nutrition médicale, la formule pour nourrissons, des compléments alimentaires, des produits nutritionnels généraux (par exemple, des boissons laitières).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)