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1. (WO2019042950) IMPROVED HIV ENVELOPE GLYCOPROTEIN IMMUNOGENS
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Pub. No.: WO/2019/042950 International Application No.: PCT/EP2018/073053
Publication Date: 07.03.2019 International Filing Date: 27.08.2018
IPC:
C07K 14/005 (2006.01) ,A61K 39/21 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
01
DNA viruses
03
Herpetoviridae, e.g. pseudorabies virus
05
Epstein-Barr virus
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
12
Viral antigens
21
Retroviridae, e.g. equine infectious anemia virus
Applicants:
ACADEMISCH MEDISCH CENTRUM [NL/NL]; Meibergdreef 9 1105 AZ Amsterdam, NL
Inventors:
MEDINA-RAMIREZ, Max; NL
SANDERS, Rogier; NL
Agent:
DE PAUW, Elmar; NL
Priority Data:
17188050.326.08.2017EP
Title (EN) IMPROVED HIV ENVELOPE GLYCOPROTEIN IMMUNOGENS
(FR) IMMUNOGÈNES GLYCOPROTÉIQUES D'ENVELOPPE DE VIH AMÉLIORÉS
Abstract:
(EN) The invention relates to an isolated, recombinant or synthetic polypeptide comprising an Env polypeptide of an HIV virus, the Env polypeptide comprising at least the amino acid residues K275, D276 and R278, wherein said numbering is according to the HxB2 reference sequence having the amino acid sequence of SEQ ID NO: 1.
(FR) L'invention concerne un polypeptide isolé, recombinant ou synthétique comprenant un polypeptide d'env d'un virus VIH, le polypeptide d'env comprenant au moins les résidus d'acides aminés K275, D276 et R278, ladite numérotation étant selon la séquence de référence HxB2 ayant la séquence d'acides aminés SEQ ID NO : 1.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)