Processing

Please wait...

Settings

Settings

Goto Application

1. WO2019042447 - NOVEL TOXIN AND METHOD FOR PREPARING INTERMEDIATE THEREOF

Publication Number WO/2019/042447
Publication Date 07.03.2019
International Application No. PCT/CN2018/103781
International Filing Date 03.09.2018
IPC
C07D 207/448 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
207Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
44having three double bonds between ring members or between ring members and non-ring members
444having two doubly-bound oxygen atoms directly attached in positions 2 and 5
448with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
C07D 403/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07K 16/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
CPC
C07D 207/448
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
207Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
44having three double bonds between ring members or between ring members and non-ring members
444having two doubly-bound oxygen atoms directly attached in positions 2 and 5
448with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
C07D 403/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07K 16/30
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
Y02P 20/55
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
20Technologies relating to chemical industry
50Improvements relating to the production of products other than chlorine, adipic acid, caprolactam, or chlorodifluoromethane, e.g. bulk or fine chemicals or pharmaceuticals
55Synthetic design, e.g. reducing the use of auxiliary or protecting groups
Applicants
  • 江苏恒瑞医药股份有限公司 JIANGSU HENGRUI MEDICINE CO., LTD. [CN]/[CN]
  • 上海恒瑞医药有限公司 SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. [CN]/[CN]
Inventors
  • 许建烟 XU, Jianyan
  • 章瑛 ZHANG, Ying
  • 屈博磊 QU, Bolei
  • 蒋贵阳 JIANG, Guiyang
Agents
  • 北京戈程知识产权代理有限公司 GE CHENG & CO., LTD.
Priority Data
201710785396.904.09.2017CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) NOVEL TOXIN AND METHOD FOR PREPARING INTERMEDIATE THEREOF
(FR) NOUVELLE TOXINE ET PROCÉDÉ DE PRÉPARATION D'UN INTERMÉDIAIRE DE CELLE-CI
(ZH) 一种新毒素及其中间体的制备方法
Abstract
(EN)
A novel toxin and a method for preparing an intermediate thereof. Specifically provided are a compound as represented by formula (III) and a method for preparing same, and a method for preparing a compound as represented by formula (I) which is obtained from the compound as represented by formula (III) by means of a series of protecting group introduction, protecting group removal, and condensation reactions.
(FR)
L'invention concerne une nouvelle toxine et un procédé de préparation d'un intermédiaire de celle-ci. L'invention concerne particulièrement un composé représenté par la formule (III) et son procédé de préparation, ainsi qu'un procédé de préparation d'un composé tel que représenté par la formule (I) obtenu à partir du composé tel que représenté par la formule (III) au moyen de l'introduction d'une série de groupes protecteurs, de l'élimination de groupes protecteurs et de réactions de condensation.
(ZH)
一种新毒素及其中间体的制备方法,具体包括通式(III)化合物及其制备方法,以及通式(III)化合物经过一系列的上保护基、脱保护基和缩合反应得到通式(I)化合物的制备方法。
Also published as
Latest bibliographic data on file with the International Bureau