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1. (WO2019042443) COMPOUND HAVING TYROSINE PROTEIN KINASE JAK3-DEGRADATION ACTIVITY
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/042443 International Application No.: PCT/CN2018/103708
Publication Date: 07.03.2019 International Filing Date: 02.09.2018
IPC:
C07D 487/04 (2006.01) ,C07D 401/14 (2006.01) ,A61K 31/519 (2006.01) ,A61P 29/00 (2006.01) ,A61P 35/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
14
containing three or more hetero rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29
Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
Applicants:
上海美志医药科技有限公司 SHANGHAI MEIZER PHARMACEUTICALS CO., LTD. [CN/CN]; 中国上海市 浦东新区万祥镇宏祥北路83弄1-42号20幢118室 Room 118 Building 20, No. 1-42, Lane 83, Hongxiang North Road Wanxiang Town, Pudong New Area Shanghai 201313, CN
Inventors:
舒永志 SHU, Yongzhi; CN
Agent:
上海德禾翰通律师事务所 DEHEHANTONG LAW FIRM; 中国上海市 徐汇区宜山路425号光启城2102室 Room 2102 21st Floor, Pole Tower, No. 425 YiShan RD Xuhui District Shanghai 200233, CN
Priority Data:
201710783074.003.09.2017CN
Title (EN) COMPOUND HAVING TYROSINE PROTEIN KINASE JAK3-DEGRADATION ACTIVITY
(FR) COMPOSÉ AYANT UNE ACTIVITÉ DE DÉGRADATION DE LA PROTÉINE TYROSINE KINASE JAK3
(ZH) 一类具有降解酪氨酸蛋白激酶JAK3活性的化合物
Abstract:
(EN) A compound having tyrosine protein kinase JAK3-degradation activity. The structural formula of the compound is as shown by formula I. The compound can be used for preparing drugs for treatment of JAK3-related diseases.
(FR) L'invention concerne un composé ayant une activité de dégradation de la protéine tyrosine kinase JAK3. La formule structurale du composé est représentée par la formule I. Le composé peut être utilisé pour préparer des médicaments pour le traitement de maladies liées à JAK3. (I)
(ZH) 一种具有降解酪氨酸蛋白激酶JAK3活性的化合物,所述化合物结构式如式I所示,其可以用于制备治疗JAK3相关疾病的药物。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)