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1. (WO2019042119) ANTIBODY AGAINST HUMAN CD47 AND USE THEREOF
Latest bibliographic data on file with the International Bureau    Submit observation

Pub. No.: WO/2019/042119 International Application No.: PCT/CN2018/100262
Publication Date: 07.03.2019 International Filing Date: 13.08.2018
IPC:
C07K 16/28 (2006.01) ,C12N 15/13 (2006.01) ,A61P 35/00 (2006.01) ,A61K 39/395 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
12
Genes encoding animal proteins
13
Immunoglobulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Applicants:
北京智仁美博生物科技有限公司 BEIJING WISDOMAB BIOTECHNOLOGY CO., LTD [CN/CN]; 中国北京市 经济技术开发区科创六街88号A3-501 Unit A3-501 No. 88 Kechuang 6th Street, Beijing Economic And Techonological Development Area Beijing 101111, CN
智翔(上海)医药科技有限公司 GENRIX (SHANGHAI) BIOPHARMACEUTICAL CO. LTD. [CN/CN]; 中国上海市 浦东张江高科技园区牛顿路200号8号楼502 Room 502, Building No. 8 No. 200 Niudun Road, Zhang Jiang High-Tech Park, Pudong District Shanghai 201203, CN
重庆智翔金泰生物制药有限公司 CHONGQING GENRIX BIOPHARMACEUTICAL CO., LTD. [CN/CN]; 中国重庆市 江北区金源路7号楼21楼 Floor 21, Building No. 7 Jinyuan Road, Jiangbei District Chongqing 400020, CN
Inventors:
刘志刚 LIU, Zhigang; CN
刘玉兰 LIU, Yulan; CN
郭晶晶 GUO, Jingjing; CN
郝小勃 HAO, Xiaobo; CN
万姝南 WAN, Shunan; CN
胡俊杰 HU, Junjie; CN
Agent:
北京英赛嘉华知识产权代理有限责任公司 INSIGHT INTELLECTUAL PROPERTY LIMITED; 中国北京市 海淀区知春路甲48号盈都大厦A座19A 19 A, Tower A, InDo Building No. 48A Zhichun Road, Haidian District Beijing 100098, CN
Priority Data:
201710777971.001.09.2017CN
201810375653.620.04.2018CN
Title (EN) ANTIBODY AGAINST HUMAN CD47 AND USE THEREOF
(FR) ANTICORPS DIRIGÉ CONTRE CD47 HUMAIN ET SON UTILISATION
(ZH) 抗人CD47抗体及其用途
Abstract:
(EN) The present application discloses an antibody or an antigen-binding moiety thereof that specifically binds to human CD47, a polynucleotide encoding the antibody or the antigen-binding moiety thereof, a vector comprising the polynucleotide, a host cell comprising the polynucleotide or the vector, a method for preparing and purifying the antibody, and an application of the antibody or the antigen-binding moiety thereof.
(FR) La présente invention concerne un anticorps ou une fraction de liaison à l'antigène de celui-ci qui se lie de manière spécifique à CD47 humain, un polynucléotide codant pour l'anticorps ou la fraction de liaison à l'antigène de celui-ci, un vecteur comprenant le polynucléotide, une cellule hôte comprenant le polynucléotide ou le vecteur, un procédé de préparation et de purification de l'anticorps, et une application de l'anticorps ou de la fraction de liaison à l'antigène de celui-ci.
(ZH) 本申请公开了特异性结合人CD47的抗体或其抗原结合部分,编码所述抗体或其抗原结合部分的多核苷酸、包含所述多核苷酸的载体、包含所述多核苷酸或载体的宿主细胞、制备和纯化该抗体的方法及所述抗体或其抗原结合部分的应用。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)