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1. (WO2019041405) APPLICATION OF IBANDRONATE, POWDER SPRAY AND METHOD FOR PREPARING THE SAME
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Pub. No.: WO/2019/041405 International Application No.: PCT/CN2017/102755
Publication Date: 07.03.2019 International Filing Date: 21.09.2017
IPC:
A61K 31/663 (2006.01) ,A61K 9/72 (2006.01) ,A61K 47/26 (2006.01) ,A61P 11/00 (2006.01) ,A61P 11/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
662
Phosphorus acids or esters thereof having P-C bonds, e.g. foscarnet, trichlorfon
663
Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
72
for smoking or inhaling
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
06
Organic compounds
26
Carbohydrates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
Applicants:
杭州旦承医药科技有限公司 HANGZHOU DC PHARMACEUTICAL CO. LTD. [CN/CN]; 中国浙江省杭州市 经济技术开发区下沙街道新元金沙城5幢2单元411室 Room 411, Unit 2, 5# Building, Xinyuan Jinsha Community Xiasha Street, Economic and Technological Development Zone Hangzhou, Zhejiang 310000, CN
Inventors:
陈燃 CHEN, Ran; CN
陆泉 LU, Quan; CN
栗波 LI, Bo; CN
Agent:
深圳市恒申知识产权事务所(普通合伙) HENSEN INTELLECTUAL PROPERTY FIRM; 中国广东省深圳市 福田区南园路68号上步大厦10H 10H Shangbu Building No.68 Nanyuan Road, Futian Shenzhen, Guangdong 518000, CN
Priority Data:
201710786546.804.09.2017CN
Title (EN) APPLICATION OF IBANDRONATE, POWDER SPRAY AND METHOD FOR PREPARING THE SAME
(FR) APPLICATION D’IBANDRONATE, AGENT DE PROJECTION DE POUDRE ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(ZH) 伊班膦酸钠的用途及粉雾剂和制备方法
Abstract:
(EN) Disclosed are an application of Ibandronate for treating chronic obstructive pulmonary disease and/or asthma, and a powder spray or atomized liquid drops containing Ibandronate wherein the particle size of the Ibandronate micro-powder contained in the powder spray is 2.5-10 μm, and the particle size distribution d90 is greater than or equal to 7 μm; the atomized liquid drops containing Ibandronate are dissolved in a PBS solution, and the size of the atomized liquid drops is less than or equal to 7 μm.
(FR) Font l’objet de la présente invention une application d’Ibandronate pour le traitement de la broncho-pneumopathie chronique obstructive et/ou l'asthme, ainsi qu’un agent de projection de poudre ou de gouttes liquides atomisées contenant un Ibandronate dont la granulométrie de la micropoudre d'Ibandronate vaporisé est comprise entre 2,5 et 10 μm et dont la distribution granulométrique d90 est supérieure ou égale à 7 μm. Les gouttes atomisées contiennent un Ibandronate et sont dissoutes dans une solution PBS, et la taille des gouttes atomisées est inférieure ou égale à 7 μm.
(ZH) 伊班膦酸钠治疗慢性阻塞性肺疾病和/或哮喘的用途以及包含伊班膦酸钠的粉雾剂或雾化液滴;所述粉雾剂中伊班膦酸钠微粉的粒度为2.5μm-10μm,粒度分布d90≤7μm;所述雾化液滴为伊班膦酸钠溶于PBS溶液中,雾化液滴颗粒大小≤7μm。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)