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1. (WO2019040994) "IMMUNOREGULATORY MOLECULES AND USES THEREFOR"
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Pub. No.: WO/2019/040994 International Application No.: PCT/AU2018/050944
Publication Date: 07.03.2019 International Filing Date: 31.08.2018
IPC:
A61K 38/16 (2006.01) ,A61P 37/00 (2006.01) ,A61P 35/02 (2006.01) ,C07K 14/475 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37
Drugs for immunological or allergic disorders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
02
specific for leukemia
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
Applicants:
THE AUSTRALIAN NATIONAL UNIVERSITY [AU/AU]; The Australian National University Canberra, Australian Capital Territory 0200, AU
Inventors:
GARCIA DE VINUESA DE LA CONCHA, Maria Carola; AU
GONZALEZ-FIGUEROA, Paula Carolina Cecilia; AU
Agent:
DAVIES COLLISON CAVE PTY LTD; 10/301 Coronation Drive Milton, Queensland 4064, AU
Priority Data:
201790353801.09.2017AU
Title (EN) "IMMUNOREGULATORY MOLECULES AND USES THEREFOR"
(FR) MOLÉCULES IMMUNORÉGULATRICES ET LEURS UTILISATIONS
Abstract:
(EN) Disclosed are agents and methods for treating unwanted or deleterious immune responses. More particularly, the present invention discloses neuritin agents for use in inhibiting plasma cell (PC) differentiation, reducing the number of autoreactive B cells, treating, or inhibiting the development or progression of, autoreactive B cell disorders including B cell-mediated autoimmune diseases and IgE-mediated disorders and of monoclonal gammopathies and PC dyscrasias.
(FR) L'invention concerne des agents et des méthodes pour traiter des réponses immunitaires indésirables ou délétères. Plus particulièrement, la présente invention concerne des agents de neuritine destinés à être utilisés dans l'inhibition de la différenciation de cellules plasmatiques (CP), la réduction du nombre de cellules B auto-réactives, le traitement, ou l'inhibition du développement ou de la progression de troubles de cellules B auto-réactives comprenant des maladies auto-immunes médiées par des cellules B et des troubles médiés par IgE et des gammopathies monoclonales et des dyscrasies de CP.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)