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1. (WO2019039540) CYTOCIDAL AGENT
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/039540 International Application No.: PCT/JP2018/031136
Publication Date: 28.02.2019 International Filing Date: 23.08.2018
Chapter 2 Demand Filed: 09.01.2019
IPC:
A61K 38/10 (2006.01) ,A01K 67/027 (2006.01) ,A61K 47/66 (2017.01) ,A61P 15/00 (2006.01) ,A61P 35/00 (2006.01) ,A61P 43/00 (2006.01) ,C07K 7/08 (2006.01) ,C07K 19/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
04
Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
10
Peptides having 12 to 20 amino acids
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
K
ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67
Rearing or breeding animals, not otherwise provided for; New breeds of animals
027
New breeds of vertebrates
[IPC code unknown for A61K 47/66]
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
7
Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
04
Linear peptides containing only normal peptide links
08
having 12 to 20 amino acids
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
Applicants:
学校法人藤田学園 FUJITA ACADEMY [JP/JP]; 愛知県豊明市沓掛町田楽ヶ窪1番地98 1-98, Dengakugakubo, Kutsukake-cho, Toyoake-shi, Aichi 4701192, JP
Inventors:
杉原 一廣 SUGIHARA Kazuhiro; JP
金山 尚裕 KANAYAMA Naohiro; JP
小野寺 雄一郎 ONODERA Yuichiro; JP
柴田 俊章 SHIBATA Toshiaki; JP
福田 道子 FUKUDA Michiko; JP
野中 元裕 NONAKA Motohiro; JP
Agent:
棚井 澄雄 TANAI Sumio; JP
松沼 泰史 MATSUNUMA Yasushi; JP
田▲崎▼ 聡 TAZAKI Akira; JP
小林 淳一 KOBAYASHI Junichi; JP
大槻 真紀子 OTSUKI Makiko; JP
Priority Data:
2017-16155624.08.2017JP
Title (EN) CYTOCIDAL AGENT
(FR) AGENT CYTOCIDE
(JA) 細胞殺傷剤
Abstract:
(EN) The present invention pertains to: a cytocidal agent which comprises a peptide comprising the amino acid sequence represented by SEQ ID NO: 1 and a site capable of selectively binding to a target molecule; and the cytocidal agent wherein the peptide comprising the amino acid sequence represented by SEQ ID NO: 1 is a peptide consisting exclusively of L-amino acids, a peptide wherein, in the amino acid sequence represented by SEQ ID NO: 1, the 1st to 14th amino acids are D-amino acids and the 15th to 19th amino acids are L-amino acids, a peptide wherein, in the amino acid sequence represented by SEQ ID NO: 1, the 1st to 14th amino acids are L-amino acids and the 15th to 19th amino acids are D-amino acids, or a peptide consisting exclusively of D-amino acids.
(FR) La présente invention concerne : un agent cytocide qui comprend un peptide comprenant la séquence d'acides aminés représentée par SEQ ID NO : 1 et un site capable de se lier de façon sélective à une molécule cible ; et l'agent cytocide dans lequel le peptide comprenant la séquence d'acides aminés représentée par SEQ ID NO : 1 est un peptide exclusivement constitué d'acides L-aminés, un peptide dans lequel, dans la séquence d'acides aminés représentée par SEQ ID NO : 1, les acides aminés 1 à 14 sont des acides D-aminés et les acides aminés 15 à 19 sont des acides L-aminés, un peptide dans lequel, dans la séquence d'acides aminés représentée par SEQ ID NO : 1, les acides aminés 1 à 14 sont des acides L-aminés et les acides aminés 15 à 19 sont des acides D-aminés, ou un peptide exclusivement constitué d'acides D-aminés.
(JA) 本発明は、配列番号1で表されるアミノ酸配列からなるペプチドと、標的分子と選択的に結合する部位とを有する、細胞殺傷剤、前記配列番号1で表されるアミノ酸配列からなるペプチドが、全てL-アミノ酸からなるペプチド、配列番号1で表されるアミノ酸配列のうち、1~14番目のアミノ酸までがD-アミノ酸からなり、15~19番目のアミノ酸までがL-アミノ酸からなるペプチド、配列番号1で表されるアミノ酸配列のうち、1~14番目のアミノ酸までがL-アミノ酸からなり、15~19番目のアミノ酸までがD-アミノ酸からなるペプチド、又は全てD-アミノ酸からなるペプチドである、前記記載の細胞殺傷剤である。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)