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1. (WO2019033585) METHOD FOR EXTRACTING OAT ALKALOID, AND SPRAY AND PREPARATION METHOD THEREFOR
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Pub. No.: WO/2019/033585 International Application No.: PCT/CN2017/109786
Publication Date: 21.02.2019 International Filing Date: 07.11.2017
IPC:
A61K 36/899 (2006.01) ,A61K 9/12 (2006.01) ,A61P 17/00 (2006.01) ,A61K 31/4166 (2006.01) ,A61K 31/704 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36
Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18
Magnoliophyta (angiosperms)
88
Liliopsida (monocotyledons)
899
Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
10
Dispersions; Emulsions
12
Aerosols; Foams
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17
Drugs for dermatological disorders
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4164
1,3-Diazoles
4166
having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
70
Carbohydrates; Sugars; Derivatives thereof
7028
Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7034
attached to a carbocyclic compound, e.g. phloridzin
704
attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
Applicants:
广州无添加主义化妆品有限公司 GUANGZHOU ADDITIVE FREE COSMETIC CO., LTD. [CN/CN]; 中国广东省广州市 高新技术产业开发区科丰路31号自编二栋华南新材料创新园G7栋201号 Rm. 201, Block G7, South China New Materials Innovation Park, Building 2, No. 31, Kefeng Rd. Hi-Tech Industry Development Zone Guangzhou, Guangdong 510000, CN
Inventors:
杨志喜 YANG, Zhixi; CN
Agent:
北京超凡志成知识产权代理事务所(普通合伙) CHOFN INTELLECTUAL PROPERTY; 中国北京市 海淀区北四环西路68号左岸工社1215-1218室 Room 1215-1218, Floor 12 Left Bank Community No.68 Beisihuanxilu Haidian District Beijing 100080, CN
Priority Data:
201710699574.615.08.2017CN
Title (EN) METHOD FOR EXTRACTING OAT ALKALOID, AND SPRAY AND PREPARATION METHOD THEREFOR
(FR) PROCÉDÉ D'EXTRACTION D’UN ALCALOÏDE D'AVOINE, FORMULE DE PULVÉRISATION ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ
(ZH) 一种燕麦生物碱的提取方法、喷雾剂及其制备方法
Abstract:
(EN) A method for extracting an oat alkaloid, and a spray for treating dermatitis and a preparation method therefor. The method for extracting an oat alkaloid comprises: extracting oat bran using a mixed liquor of 1,2-pentanediol and 1,2-hexanediol at an extraction temperature of 50-70°C, for an extraction time of 1-3h, and, at a ratio of oat bran to mixed liquor of 1 g : 5-10 mL, obtaining a crude extract liquor; purifying and concentrating the crude extract liquor using a macroporous resin. Raw materials of the spray comprise: a first main ingredient, a second main ingredient, and an excipient. The first main ingredient comprises the oat alkaloid, 1,2-pentanediol, 1,2-hexanediol, and dipotassium glycyrrhizinate. The second main ingredient comprises allantoin and water. The excipient comprises sodium hyaluronate, 1,2-hexanediol, and water.
(FR) L'invention concerne un procédé d'extraction d'un alcaloïde d'avoine, une formule de pulvérisation pour le traitement de la dermatite et un procédé de préparation associé. Le procédé d'extraction d'un alcaloïde d'avoine selon l'invention comprend : l'extraction de son d'avoine à l'aide d'une liqueur mixte constituée de 1,2-pentanediol et de 1,2-hexanediol à une température d'extraction de 50-70 °C, pendant un temps d'extraction de 1-3 h, et, à un rapport son d'avoine à liqueur mixte de 1 g:5-10 mL, l'obtention d'une liqueur d'extrait brut ; la purification et la concentration de la liqueur d'extrait brut à l'aide d'une résine macroporeuse. Les matières premières de la formule de pulvérisation comprennent : une première substance principale, une seconde substance principale et un excipient. La première substance principale comprend l'alcaloïde d'avoine, le 1,2-pentanediol, le 1,2-hexanediol et du glycyrrhizinate dipotassique. La seconde substance principale comprend un allantoïne et de l'eau. L'excipient comprend le hyaluronate de sodium, le 1,2-hexanediol et l'eau.
(ZH) 一种燕麦生物碱的提取方法、一种治疗皮炎的喷雾剂及其制备方法。燕麦生物碱的提取方法包括:利用1,2-戊二醇和1,2-己二醇的混合液对燕麦麸皮进行提取得到粗提液,提取温度为50-70℃,提取时间为1-3h,燕麦麸皮与混合液的比例为1g:5-10mL,将粗提液经大孔树脂纯化、浓缩。喷雾剂原料包括:第一主料、第二主料和辅料,第一主料包括燕麦生物碱、1,2-戊二醇、1,2-己二醇以及甘草酸二钾。第二主料包括尿囊素和水。辅料包括透明质酸钠、1,2-己二醇以及水。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)