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1. (WO2019033336) NANOCAPSULE-BASED OCULAR THERAPY
Latest bibliographic data on file with the International BureauSubmit observation

Pub. No.: WO/2019/033336 International Application No.: PCT/CN2017/097834
Publication Date: 21.02.2019 International Filing Date: 17.08.2017
IPC:
A61F 9/008 (2006.01) ,A61K 41/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
9
Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
08
Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
41
Medicinal preparations obtained by treating materials with wave energy or particle radiation
Applicants:
XINOVA, LLC [US/US]; 311 1/2 Occidental Ave S Suite 300 Seattle, WA 98104, US
XIAO, Zhen [CN/CN]; CN (US)
Inventors:
XIAO, Zhen; CN
Agent:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENCY LTD.; 16th Fl., Block A, Corporate Square, No.35 Jinrong Street Beijing 100033, CN
Priority Data:
Title (EN) NANOCAPSULE-BASED OCULAR THERAPY
(FR) TRAITEMENT OCULAIRE À BASE DE NANOCAPSULES
Abstract:
(EN) A method of macular disease treatment(500) may include introducing nanocapsules into a body of a patient(502). The nanocapsules may be introduced such that the nanocapsules circulate through at least a portion of a body of the patient. A therapeutic substance and a colorant may be encapsulated into the nanocapsules. After a portion of the nanocapsules enters choroidal neovessels of an eye of the patient, the method may include emitting a pulsed laser radiation through a pupil of the eye(504). Additionally, after a portion of the nanocapsules enters choroidal neovessels of an eye of the patient, the method may include heating the portion of the nanocapsules present in the eye(506) such that at least a portion of the nanocapsules transfer phase and release the therapeutic substance.
(FR) L'invention concerne une méthode de traitement de la maladie maculaire (500), qui peut comprendre l'introduction de nanocapsules dans le corps d'un patient (502). Les nanocapsules peuvent être introduites de façon à ce que ces dernières circulent à travers au moins une partie du corps du patient. Une substance thérapeutique et un colorant peuvent être encapsulés dans les nanocapsules. Après qu'une partie des nanocapsules a pénétré dans les néovaisseaux choroïdiens de l'œil du patient, la méthode peut comprendre l'émission d'un rayonnement laser pulsé à travers la pupille de l'œil (504). De plus, après qu'une partie des nanocapsules a pénétré dans les néovaisseaux choroïdiens de l'œil du patient, la méthode peut comprendre le réchauffement de la partie des nanocapsules présentes dans l'œil (506) de telle sorte qu'au moins une partie des nanocapsules changent de phase et libèrent la substance thérapeutique.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)